Recreational MDMA is illegal and often contaminated with deadly fentanyl, posing extreme safety risks. The sourcing of MDMA is extremely important and its safety issues cannot be overlooked.
MDMA taken on its own does not cure PTSD; instead, it significantly boosts the effectiveness of talk therapy for PTSD by engaging specific neural circuits. This combination has shown remarkable results in clinical trials.
The clinical protocol for PTSD involves three preparatory 90-minute talk therapy sessions, followed by three 8-hour MDMA sessions (with initial and booster doses) alongside two therapists, and then three 90-minute follow-up talk therapy sessions spaced one week apart. This structured approach helps patients reframe traumatic events in a supportive environment.
Taking a Selective Serotonin Reuptake Inhibitor (SSRI) prior to MDMA can block its prosocial and empathogenic effects. These effects are crucial for the therapeutic outcomes of MDMA-assisted therapy.
Taking caffeine within hours or on the same day as MDMA can increase its potential toxicity, according to animal studies. Restricting caffeine intake on the day of and around MDMA ingestion is advantageous.
During MDMA use, avoid settings that greatly increase blood pressure or body temperature, such as hot environments or intense physical activity. Ensure adequate fluid and electrolyte intake to prevent neurotoxicity from temperature effects.
Do not take 5-HTP or L-tyrosine to buffer the post-MDMA crash, as there is no evidence of benefit and potential for detriment. These precursors could further deplete serotonin and dopamine, contrary to popular belief.
P5P (a metabolite of vitamin B6) is being explored to suppress prolactin, which is dramatically increased by MDMA and contributes to the post-MDMA crash symptoms like lethargy and lack of motivation. While human data is limited, this approach has a mechanistic basis.
Engage in talk therapy with a psychologist or psychiatrist who fosters good rapport and a supportive, safe environment. This allows for effective exploration of trauma and its impact on current behaviors and emotional states.
Engage in Non-Sleep Deep Rest (NSDR) or Yoga Nidra, even for short 10-minute sessions, to greatly restore cognitive and physical energy. The Waking Up app offers various programs for this purpose.
Dissolve one packet of Element in 16-32 ounces of water upon waking and during physical exercise. This ensures adequate hydration and electrolyte balance (sodium, magnesium, potassium) vital for optimal brain and body function.
Consume Athletic Greens (AG1) once or twice daily to support gut health with probiotics and meet foundational nutritional needs. It contains adaptogens, vitamins, and minerals crucial for overall well-being.
For a comprehensive understanding of trauma and its treatment, read Dr. Paul Conti’s book ‘Trauma.’ It provides valuable insights into the definition of trauma and effective patient care.