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BITESIZE | The Most Powerful Daily Habit for Better Brain Health | Louisa Nicola #585

Oct 9, 2025 24m 17s 14 insights
Do you think that it’s inevitable that the function of your brain will decline as you get older? Or, do you believe that there are simple things you can do each day to preserve, protect and enhance it? Feel Better Live More Bitesize is my weekly podcast for your mind, body, and heart. Each week I’ll be featuring inspirational stories and practical tips from some of my former guests. Today’s clip is from episode 522 of the podcast with neurophysiologist and brain health researcher, Louisa Nicola. Louisa believes that exercise is one of the most powerful tools we have to protect and enhance our brain health and, in this clip, she shares simple, practical strategies that we can all adopt – whatever our age or fitness level.  Louisa believes that while modern lifestyles may contribute to cognitive decline, we have far more control over our brain health than we might think. Small daily choices add up, and it’s never too early—or too late—to start. Thanks to our sponsor ⁠https://drinkag1.com/livemore⁠re⁠⁠ Show notes and the full podcast are available at https://drchatterjee.com/522 Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts ⁠⁠https://apple.co/feelbetterlivemore⁠⁠ For other podcast platforms go to ⁠⁠https://fblm.supercast.com.
Actionable Insights

1. Prioritize Exercise for Overall Health

Recognize exercise as the most impactful intervention for health, considering it a ‘panacea’ and medicine, with muscles acting as ‘pharmacies’ that release beneficial compounds.

2. Perform 3 Hours Aerobic Exercise Weekly

Engage in a minimum of three hours of aerobic exercise per week at a ‘zone two’ intensity (around 65% of your maximum heart rate), where you can converse but are slightly out of breath, to increase brain gray matter, grow new brain cells in the hippocampus, and improve mitochondrial function for more energy.

3. 20 Minutes High-Intensity Training Weekly

Incorporate 20 minutes of high-intensity training per week (Zone 4 or 5, ‘death zone’) to significantly benefit cancer outcomes and brain health by increasing natural killer cells that destroy circulating tumor cells and providing a massive blood shunt to the brain.

4. Strength Train for Overall Health

Recognize strength training as a fundamentally important part of exercise, as it increases muscle mass (which declines after age 40), stores mitochondria for energy, stabilizes the body, and releases myokines that positively impact the brain (preserving synapses, neuron survival, hippocampus growth) and other organs.

5. Prioritize Compound Strength Movements

Perform strength training at least two days a week, focusing on compound movements like squats, bench presses, and walking lunges, which engage multiple muscle groups simultaneously to maximize benefits like increasing gray matter, rather than isolated ‘aesthetics’ exercises.

6. Start Strength with Bodyweight Exercises

If new to strength training or sedentary, begin with bodyweight exercises (calisthenics) like pushups or follow beginner workout videos online, rather than feeling intimidated by gym weights, as any starting point can yield significant gains.

7. Increase Movement as You Age

Consciously prioritize daily physical activity, especially as you get older, to counteract sedentarism and maintain good brain and heart health; aim for at least an hour of walking daily as a minimum.

8. Start Moving, Any Activity Helps

If currently inactive, begin with simple movements like walking for 10 minutes a day, even on hills, as any activity will make a difference and provide benefits for brain health and mood.

9. Exercise for Health, Not Aesthetics

Shift your primary motivation for exercise from aesthetics to brain health, overall health outcomes, and longevity, as these are the most profound and lasting benefits.

10. Exercise to Improve Mood

Engage in exercise to help express BDNF and other neurochemicals, which are directly correlated with improved mood and can help combat depression by changing the brain’s structure.

11. Exercise to Increase Energy Levels

If experiencing low energy, engage in ‘zone two’ aerobic training, as it specifically trains the mitochondria (the cell’s powerhouse) to work better, function more efficiently, and create more energy.

12. Understand Individual Zone 2 Intensity

Recognize that ‘Zone 2’ exercise (65% of maximum heart rate) is individualized; for someone less metabolically fit, this might be a fast-paced walk, while for others it could be an easy jog, cycling, or using an elliptical.

13. Find Enjoyable Exercise for Consistency

Discover forms of physical activity that you genuinely love and find enjoyable to ensure consistency and make exercise a sustainable, regular part of your routine without it feeling like a chore.

14. Prevent Brain Decline Early

Understand that conditions like Alzheimer’s disease accumulate from your 20s, 30s, and 40s, and dementia is not an inevitable part of aging; proactively prioritize lifestyle factors like exercise, sleep, stress management, and food for long-term brain health.