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BITESIZE | 3 Steps to Reverse Ageing and Live Longer | Professor David Sinclair #293

Sep 8, 2022 15m 28s 8 insights
What if you could prevent ageing or even reverse it?   Feel Better Live More Bitesize is my weekly podcast for your mind, body, and heart. Each week I’ll be featuring inspirational stories and practical tips from some of my former guests.   Today’s clip is from episode 208 of the podcast with one of the world’s leading scientific authorities on ageing - biologist and Harvard professor, David Sinclair.   The key to staying young, he explains, is inducing hormesis, a state of survival in our bodies, and, in this clip, he describes some simple habits that can help to switch on our bodies’ longevity genes.   CAUTION: This podcast discusses fasting and its advice may not be suitable for anyone with an eating disorder. If you have an existing health condition or are taking medication, always consult your healthcare practitioner before going for prolonged periods without eating.   Show notes and the full podcast are available at drchatterjee.com/208 Order Dr Chatterjee's new book Happy Mind, Happy Life: UK version: https://amzn.to/304opgJ US & Canada version: https://amzn.to/3DRxjgp Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.   Follow me on instagram.com/drchatterjee Follow me on facebook.com/DrChatterjee Follow me on twitter.com/drchatterjeeuk
Actionable Insights

1. Induce Hormesis for Longevity

Actively induce hormesis by exposing your body to mild adversities like exercise and skipping meals, as this triggers ancient survival mechanisms that protect against decay, disease, and aging.

2. Practice Intermittent Fasting

Eat less often by skipping meals or snacks daily, as this boosts longevity genes and has been shown to lead to longer, healthier lives in animals, with the timing of eating being more important than what is eaten. Start by skipping one meal (dinner or breakfast) and gradually extend the fasting window as your body adapts.

3. Perform High-Intensity Exercise

Engage in high-intensity exercise that makes you lose your breath for about 10 minutes, a few times a week, as this is sufficient for long-term health benefits and helps reset muscle function.

4. Actively Reduce Chronic Stress

Actively work to reduce chronic stress by reframing challenges, finding purpose, and consciously choosing excitement and gratitude for life, as prolonged stress negatively impacts the biological clock.

5. Lift Weights to Maintain Muscle

Lift weights to build and maintain large muscles in your legs, glutes, and back, which is crucial for preventing muscle loss with age and can help raise testosterone levels by signaling to the testes.

6. Prioritize Daily Movement

Ensure you walk and move regularly as a minimum to avoid future health problems, and consider using a standing desk to build leg, glute, and back muscles.

7. Consider NMN Supplementation

Consider taking NMN, a molecule that has been shown to boost the body’s ability to make new blood vessels and improve muscle oxygen measurement, enhancing exercise capacity, but it should not replace exercise.

8. Take AG1 Daily

Consider taking AG1 daily, a health drink that supports digestion and contains five strains of gut bacteria, which can enrich the gut microbiome and impact mental and physical well-being.