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Qualy #120 - What is the difference between ketone salts and esters?

Feb 28, 2020 6m 29s 7 insights
<p><span style="font-weight: 400;">Today's episode of</span> <em><span style="font-weight: 400;">The Qualys</span></em> <span style="font-weight: 400;">is from podcast</span> <a href="https://peterattiamd.com/domdagostino/"><span style="font-weight: 400;">#05 – Dom D'Agostino, Ph.D.: ketosis, n=1, exogenous ketones, HBOT, seizures, and cancer</span></a><span style="font-weight: 400;">.</span></p> <p> </p> <p><em><span style="font-weight: 400;">The Qualys</span></em> <span style="font-weight: 400;">is a subscriber-exclusive podcast, released Tuesday through Friday, and published exclusively on our private, subscriber-only podcast feed.</span> <em><span style="font-weight: 400;">Qualys</span></em> <span style="font-weight: 400;">is short-hand for "qualifying round," which are typically the fastest laps driven in a race car</span><span style="font-weight: 400;">—</span><span style="font-weight: 400;">done before the race to determine starting position on the grid for race day.</span> <em><span style="font-weight: 400;">T</span></em><em><span style="font-weight: 400;">he Qualys</span></em> <span style="font-weight: 400;">are short (i.e., "fast"), typically less than ten minutes, and highlight the best questions, topics, and tactics discussed on</span> <em><span style="font-weight: 400;">The Drive</span></em><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">Occasionally, we will also release an episode on the main podcast feed for non-subscribers, which is what you are listening to now.</span></p> <p><span style="font-weight: 400;">Learn more:</span> <a href="https://peterattiamd.com/podcast/qualys/"><span style="font-weight: 400;">https://peterattiamd.com/podcast/qualys/</span></a><span style="font-weight: 400;">  </span></p> <p><span style="font-weight: 400;">Subscribe to receive access to all episodes of</span> <em><span style="font-weight: 400;">The Qualys</span></em> <span style="font-weight: 400;">(and other exclusive subscriber-only content):</span> <a href="https://peterattiamd.com/subscribe/"><span style="font-weight: 400;">https://peterattiamd.com/subscribe/</span></a><span style="font-weight: 400;"> </span></p> <p><span style="font-weight: 400;">Connect with Peter on</span> <a href="http://facebook.com/PeterAttiaMD%5dFacebook"><span style="font-weight: 400;">Facebook.com/PeterAttiaMD</span></a> <span style="font-weight: 400;">|</span> <a href="http://twitter.com/PeterAttiaMD%5dTwitter"><span style="font-weight: 400;">Twitter.com/PeterAttiaMD</span></a> <span style="font-weight: 400;">|</span> <a href="http://instagram.com/PeterAttiaMD%5dInstagram"><span style="font-weight: 400;">Instagram.com/PeterAttiaMD</span></a><span style="font-weight: 400;"> </span></p>
Actionable Insights

1. Seek Professional Medical Advice

Always seek the assistance of healthcare professionals for any medical conditions and do not disregard or delay obtaining professional medical advice, as the podcast content is for informational purposes only and not a substitute for medical advice.

2. Dilute Ketone Esters

If consuming ketone esters, dilute and mix them as instructed, rather than consuming a concentrated vial directly, to avoid adverse effects like the speaker’s experience of feeling like he would go blind.

3. Manage Magnesium BHB Dosage

When consuming magnesium beta-hydroxybutyrate, be aware that GI tolerability may be limited to 1-3 grams max per dose, as higher amounts can cause gastrointestinal issues.

4. Optimize Ketone Electrolyte Formulations

For ketone electrolyte formulations, ideally spread the beta-hydroxybutyrate across monovalent and divalent cations (such as sodium, potassium, calcium, and magnesium) to enhance utility.

5. Optimize Ketone Ester Potency

To achieve higher ketone levels with ketone esters, consider using the R beta-hydroxybutyrate with the R 1,3-butanediol.

6. Review Speaker Disclosures

To understand potential conflicts of interest, visit peteratiamd.com/about to review an up-to-date list of companies the speaker invests in or advises.

7. Access More Qualies Episodes

If you enjoy the Qualies, you can access dozens more bonus episodes through the membership program at peteratiamd.com/subscribe.