<p><span style="color: #000000;">In this "Ask Me Anything" (AMA) episode, Peter answers a wide range of questions from subscribers. Bob Kaplan, Peter's head of research, asks the questions. If you're not a subscriber and listening on a podcast player, you'll only be able to hear a preview of the AMA.</span><span style="color: #333333;"><br /> <br /></span><span style="color: #333333;"><span style="color: #2b2e2f;">If you're a subscriber, you can now listen to this full episode on your </span><a href="https://peterattiamd.com/members/private-podcast-feed/"><span style="color: #000000;">private RSS feed</span></a><span style="color: #2b2e2f;">. You can also listen to this full episode on our website at the AMA </span><a href="https://attiamedical.zendesk.com/agent/tickets/10"><span style="color: #000000;">#10</span></a><span style="color: #2b2e2f;"> </span><a href="https://peterattiamd.com/ama10"><span style="color: #000000;">show notes page</span></a><span style="color: #2b2e2f;">.</span><br /> <br /></span><span style="color: #000000;">We discuss:</span><span style="color: #333333;"><br /></span></p> <ul> <li><span style="color: #000000;">Does testosterone supplementation impact longevity? [2:40];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">Under what conditions does Peter decide to treat patients who have low testosterone? [8:50];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">Are there risks involved with testosterone replacement therapy? [17:10];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">How does Peter diagnose and treat hypothyroidism? [21:30];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">How might someone do time-restricted feeding while also adding muscle mass? [26:30];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">If building muscle requires higher levels of IGF-1, should we be concerned about longevity? [34:45];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">How to preserve muscle mass while fasting [41:45];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">Is it possible to simultaneously lose fat and add muscle mass? [46:30]; and</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #000000;">More.</span></li> </ul> <p><span style="color: #000000;">Learn more: <a href="https://peterattiamd.com/">https://peterattiamd.com/</a><br /> <br /> Show notes page for this episode: <a href="https://peterattiamd.com/ama10"><span style="color: #333333;">https://peterattiamd.com/ama10</span></a><br /> <br /> Subscribe to receive exclusive subscriber-only content: <a href="https://peterattiamd.com/subscribe/">https://peterattiamd.com/subscribe/</a><br /> <br /> Sign up to receive Peter's email newsletter: <a href="https://peterattiamd.com/newsletter/">https://peterattiamd.com/newsletter/</a><br /> <br /> Connect with Peter on <a href="http://Facebook.com/PeterAttiaMD"><u>Faceboo</u></a><u>k</u> | <a href="http://Twitter.com/PeterAttiaMD"><u>Twitter</u></a> | <a href="http://Instagram.com/PeterAttiaMD"><u>Instagram</u></a>.<br /></span></p>
Actionable Insights
1. Define Medical Intervention Outcomes
Before manipulating any medical variable, ask yourself what the desired outcome is, such as improving longevity, lifespan, or healthspan, to guide your medical decisions.
2. Evaluate TRT for Physical Health
Consider testosterone replacement therapy if your goal is to improve or maintain lean muscle mass, strength, conditioning, and recovery from exercise, as these are areas where its benefits are undeniable.
3. Evaluate TRT for Emotional Well-being
If you are experiencing low mood or diminished libido, consider testosterone replacement therapy, as it can improve these aspects and potentially enhance relationships and overall life quality.
4. Prioritize Muscle Mass for Safety
Improve muscle mass and functional strength, potentially aided by testosterone replacement therapy, to help prevent accidental death later in life, which is a significant cause of mortality in older age.
5. Subscribe for Exclusive Content
To gain full access to Ask Me Anything episodes, detailed show notes, member-only discount codes, and other benefits, subscribe at peteratiamd.com/subscribe.
6. Sign Up for Weekly Insights
Subscribe to the once-a-week email at peteratiamd.com to receive updates on longevity, science, performance, sleep, and interesting papers.
Connect with Peter Attia on Twitter, Instagram, and Facebook using the ID @peteratiamd, noting that Twitter is generally the best platform for sharing questions and comments.
8. Access Episode Resources
Visit peteratiamd.com/podcast for show notes, readings, and links related to episodes, and explore the blog for additional information.