← The Peter Attia Drive

#73 - AMA #9: NAD & metformin, fat-burning zone, creatine, estrogenization of men, emergency kit for cold & flu, and more

Sep 30, 2019 16m 8s 15 insights
<p><span style="color: #201f1e;">In this "Ask Me Anything" (AMA) episode, Peter answers a wide range of questions from subscribers. Bob Kaplan, Peter's head of research, asks the questions. If you're not a subscriber and listening on a podcast player, you'll only be able to hear a preview of the AMA.</span><span style="color: #333333;"><br /> <br /></span><span style="color: #201f1e;">If you're a subscriber, you can now listen to this full episode on your <a href="https://peterattiamd.com/members/private-podcast-feed/">private RSS feed</a>. You can also watch (or listen) to this full episode on our website at the AMA #9 <a href="https://peterattiamd.com/ama09">show notes page</a>.</span><span style="color: #333333;"><br /> <br /></span><span style="color: #201f1e;">Questions continue to be pulled from the <a href="https://peterattiamd.com/ask-me-anything/">AMA section</a> on the website, and any subscriber is welcome to submit questions for future AMAs.</span><span style="color: #333333;"><br /> <br /></span><span style="color: #201f1e;">We discuss:</span><span style="color: #333333;"><br /> <br /></span></p> <ul> <li><span style="color: #201f1e;">The story of how Peter almost worked for Theranos [2:00];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">The trend of lower testosterone and higher estrogen in men: Why is it happening and what to do about it? [10:00];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">Takeaways from Peter's recent hunting trip in Hawaii [14:45];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">What books are you currently reading/listening to? [21:30];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">What advice would you give to the 25 year-old Peter? [24:00];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">What is your emergency protocol if you start getting sick? [27:45];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">How have your thoughts changed on NAD precursors, and also on metformin, in the past year or so? [30:30];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">What are your thoughts on "fat burning" zones for cardio workouts? — A lesson in relative vs. absolute fat combustion [34:15];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">What mental models do you use and how do you go about solving problems and approaching difficult questions? [49:00];</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">Creatine supplementation—Yay or nay? Why? [49:30]; and</span><span style="color: #333333;"><br /></span></li> <li><span style="color: #201f1e;">More.</span></li> </ul> <p>Learn more: <a href="https://peterattiamd.com/">https://peterattiamd.com/</a><br /> <br /> Show notes page for this episode: <a href="https://peterattiamd.com/ama08/">https://peterattiamd.com/ama09/</a><br /> <br /> Subscribe to receive exclusive subscriber-only content: <a href="https://peterattiamd.com/subscribe/">https://peterattiamd.com/subscribe/</a><br /> <br /> Sign up to receive Peter's email newsletter: <a href="https://peterattiamd.com/newsletter/">https://peterattiamd.com/newsletter/</a><br /> <br /> Connect with Peter on <a href="http://Facebook.com/PeterAttiaMD"><u>Faceboo</u></a><u>k</u> | <a href="http://Twitter.com/PeterAttiaMD"><u>Twitter</u></a> | <a href="http://Instagram.com/PeterAttiaMD"><u>Instagram</u></a>.<br /> <br /></p>
Actionable Insights

1. Evaluate Startup Opportunities Critically

When considering joining a startup, perform thorough due diligence on investors and trust feedback from your network, as these factors are crucial.

2. Maintain High Job Hurdle Rate

If you love your current job, set a very high ‘hurdle rate’ for any new opportunity, meaning it must be significantly better to warrant leaving.

3. Apply Critical Thinking to Technology

Use your domain expertise and critical thinking to evaluate new technologies and claims, especially if details are secretive or the underlying science seems implausible.

4. Prioritize Trust as Content Creator

As a content creator, prioritize audience trust by avoiding paid endorsements for products you don’t genuinely believe in or are paid to promote.

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8. Download Members-Only Podcast Feed

If you are a subscriber, download the members-only podcast feed to get every episode of the Drive without subscriber call-outs, plus full AMA episodes and other exclusive content.

9. Participate in AMA Forum

Subscribers are encouraged to participate in the AMA forum and ask questions, as these questions will be pulled for future Ask Me Anything episodes.

10. Be Aware of Hindsight Bias

Recognize hindsight bias, which causes people to believe past events were more predictable after they have occurred, when evaluating past decisions.

11. Seek Professional Medical Advice

Always seek professional medical advice for any health conditions and do not use podcast content as a substitute for diagnoses or treatment.

12. Review Conflicts of Interest

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