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#259 - Women's sexual health: Why it matters, what can go wrong, and how to fix it | Sharon Parish, M.D.

Jun 19, 2023 2h 48m 28 insights
<p><a href="https://peterattiamd.com/sharonparish/?utm_source=podcast-feed&amp;utm_medium=referral&amp;utm_campaign=230619-pod-sharonparish&amp;utm_content=230619-pod-sharonparish-podfeed"> View the Show Notes Page for This Episode</a></p> <p><a href="https://peterattiamd.com/subscribe/?utm_source=podcast-feed&amp;utm_medium=referral&amp;utm_campaign=230410-pod-sharonparish&amp;utm_content=230619-pod-sharonparish-podfeed"> Become a Member to Receive Exclusive Content</a></p> <p><a href="https://peterattiamd.com/newsletter/?utm_source=podcast-feed&amp;utm_medium=referral&amp;utm_campaign=230619-pod-sharonparish&amp;utm_content=230619-pod-sharonparish-podfeed"> Sign Up to Receive Peter's Weekly Newsletter</a></p> <p>Sharon Parish is a Professor of Medicine in Clinical Medicine and Clinical Psychiatry at Weill Cornell Medical College and a prominent sexual medicine specialist who has been practicing for 30 years. In this episode, Sharon tackles the topic of women's sexual health, including the conditions associated with decreased sexual function and desire and available treatment options. She explores the influence of sexual health on overall well-being while also examining the potential effects of childbirth, birth control, metabolic health, and more on sexual function and desire. Through case studies, Sharon teases apart the differences between desire and arousal, explains the various factors that affect them, and walks through hypothetical treatment plans for the case study patients. In addition, she delves into the subject of menopause, addressing its impact on sexual health as well as the misguided fears around hormone replacement therapy. Stay tuned for next week's launch of our complementary podcast on men's sexual health.</p> <p><strong>We discuss:</strong></p> <ul type="disc"> <li>Sharon's interest in sexual medicine and the current state of the field [3:00];</li> <li>How hormones change in women over time and how that impacts sexual function [8:15];</li> <li>Changes after childbirth and its impact on sexual function [11:00];</li> <li>The role of metabolic health and systemic vascular health in sexual health [20:15];</li> <li>Conditions associated with decreased sexual function and the importance of sexual health for overall wellbeing [26:15];</li> <li>Sexual dysfunction case study #1: A 41-year-old mother of two, the sexual response cycle, and the difference between arousal and desire [38:45];</li> <li>Medications that may reduce sexual desire [49:45];</li> <li>The effect of birth control pills on sexual desire [56:30];</li> <li>The importance of testosterone in women for sexual function and desire, and why the FDA hasn't approved exogenous testosterone as a therapeutic [1:01:15];</li> <li>Challenges faced by physicians who are open to prescribing off-label testosterone for women, and Sharon's approach in managing this aspect with her patients [1:14:30];</li> <li>A hypothetical treatment plan for the patient in case study #1 [1:26:45];</li> <li>The role of DHEA (a precursor to testosterone) in female sexual health [1:32:15];</li> <li>Case study #2: A 30-year-old woman with anorgasmia (inability to orgasm) [1:38:30];</li> <li>Resources for helping women and their partners to enhance the pleasure experienced during sex, overcome anxiety, and increase desire [1:51:30];</li> <li>Two drugs for premenopausal women with low desire [1:59:30];</li> <li>Why treatments are potentially underutilized for both desire and genitourinary syndrome of menopause [2:13:15];</li> <li>Case study #3: A menopausal woman with symptoms [2:19:00];</li> <li>Addressing the misguided fears around hormone replacement therapy and cancer [2:24:15];</li> <li>Symptoms and treatment of genitourinary syndrome of menopause [2:32:45];</li> <li>Age 65 and beyond, and resources for finding a provider [2:37:30]; and</li> <li>More.</li> </ul> <p>Connect With Peter on <a href="https://twitter.com/PeterAttiaMD">Twitter</a>, <a href="https://www.instagram.com/peterattiamd/">Instagram</a>, <a href="https://www.facebook.com/peterattiamd/">Facebook</a> and <a href="https://www.youtube.com/channel/UC8kGsMa0LygSX9nkBcBH1Sg">YouTube</a></p>
Actionable Insights

1. Prioritize Sexual Health for Wellbeing

Validate the importance of sexual function for overall quality of life, as this legitimizes seeking treatment and making lifestyle changes to improve happiness and well-being.

2. Manage Metabolic Health for Sex

Actively manage lifestyle and chronic conditions like diabetes and cardiovascular issues, as poor metabolic and vascular health are strongly linked to sexual dysfunction in both men and women.

3. Consider Menopausal Hormone Therapy

For post-menopausal women with disruptive hot flashes and night sweats, consider combined estrogen-progesterone therapy (or estrogen alone if no uterus) as it is the most effective treatment for symptom relief and is safe at low doses for short-term use.

4. Debunk HRT Breast Cancer Fears

Understand that modern bioidentical, lower-dose, transdermal hormone replacement therapy (HRT) has a much safer breast cancer profile than previously thought, with re-analysis of older studies showing minimal absolute risk and no increase in mortality.

5. HRT for Bone Health

Prioritize hormone replacement therapy for bone health and fracture prevention, as the risk of death from fractures later in life significantly outweighs the risk of death from breast cancer due to hormones.

6. Treat Vaginal Dryness Promptly

Seek treatment for vaginal dryness and discomfort, as it is one of the most treatable and manageable sexual health conditions with clear therapeutic options available.

7. Multi-Tool Approach for Vaginal Dryness

For vaginal dryness, pain with sexual activity, or genitourinary symptoms, use a multi-pronged approach including lubricants during sex, regular vaginal moisturizers, dilators for tightness, vibrators for enhanced stimulation, and consistent sexual activity.

8. Seek Postpartum Sexual Health Help

If breastfeeding and experiencing vaginal dryness, difficulty, pain, or low sexual function for six months or more without menses, consult a doctor as these symptoms are treatable and similar to post-menopausal changes.

9. Evaluate Contraception for Sexual Health

Be aware that combined hormonal contraception, especially ultra-low dose estrogen pills, can cause pain, mood issues, and lower free testosterone, impacting sexual desire and function. Discuss these potential effects with your doctor.

10. Demand Informed Contraception Choice

Seek informed consent about all contraception options and their potential impact on sexual health from your doctor, rather than just accepting a prescription, to make choices that align with your overall well-being.

11. Treat Depression for Sexual Function

Prioritize treating depression, as improving mental health often leads to better sexual function; if sexual dysfunction persists, discuss switching antidepressant medications with your doctor.

12. Explore Orgasm Stimulation Techniques

For anorgasmia, explore various stimulation techniques (clitoral, vaginal, vibrators, nipple stimulation) and learn what works best for your body, then communicate these preferences effectively to your partner.

13. Use Orgasm Education Resources

Utilize recommended books (e.g., ‘For Yourself,’ ‘Becoming Orgasmic,’ ‘The Joy of Sex’) and websites like OMGSYES.com to learn about female sexual anatomy and effective stimulation techniques for achieving orgasm.

14. Address Sexual Performance Anxiety

If experiencing performance anxiety or spectatoring during sex, consider sensate focus therapy, which gradually reintroduces sexual and partner communication in a non-threatening way.

15. Address Psychological Barriers to Sex

Seek psychological therapy if deep-seated issues like sexual trauma, genital aversion, PTSD, or strong religious/cultural prohibitions are interfering with sexual quality of life.

16. Testosterone for Female Low Desire

For post-menopausal women with distressing low desire, testosterone can be prescribed off-label using one-tenth of the male transdermal dose, prioritizing transdermal products and monitoring levels to stay within the physiologic range.

17. Safe Topical Testosterone Application

Apply topical testosterone to a relatively hairless area like the buttock, outer thigh, or back of the calf, avoiding washing for a couple of hours and ensuring no transfer to children or partners.

18. Reliable Contraception with Testosterone

Women of reproductive age using testosterone therapy must be on reliable contraception to prevent pregnancy, as testosterone use during pregnancy is not recommended.

19. Consider Flibanserin for Low Desire

For pre-menopausal women with distressing low desire, after addressing other factors, consider Flibanserin (Addyi), a daily 100mg bedtime pill that is FDA-approved and can improve desire and sexual events in 4-12 weeks.

20. Consider Bremelanotide for Low Desire

For pre-menopausal women with distressing low desire, consider Bremelanotide (Vyleesi), a self-injected on-demand treatment taken 45 minutes before sexual activity, which stimulates dopaminergic pathways to increase desire and arousal. Limit use to four times a month to reduce hyperpigmentation risk.

21. Vaginal DHEA for Atrophy

Consider intravaginal DHEA (Intrarosa) as an option for vulvovaginal atrophy and associated pain, especially post-menopause, as it has good efficacy and safety data with minimal systemic absorption.

22. Choose Transdermal HRT for VTE

For women considering hormone replacement therapy, opt for transdermal estrogen products (patches or gels) over oral formulations to potentially lower the risk of venous thromboembolism.

23. IUD for HRT Endometrial Protection

When using systemic estrogen with an intact uterus, a progesterone-coated IUD (like Mirena) can be considered as an off-label but clinically supported alternative for endometrial protection.

24. Manage Lifestyle for Menopause

Assess and manage lifestyle factors such as body weight, exercise, sleep, and relationship stress, as they can significantly influence the experience and distress of menopausal symptoms and overall sexual health.

25. Avoid Irritating Vaginal Products

Avoid warming liquids and scented products for vaginal care, as the sensitive tissue can be irritated by chemicals in these products.

26. Avoid Oral DHEA for Low Desire

Do not use oral DHEA for low sexual desire, as studies have not convincingly demonstrated its efficacy or safety for this indication.

27. Seek Sexual Medicine Specialists

To find specialized care for sexual health concerns, look for ‘sexual medicine specialist,’ ‘menopause specialist,’ ‘pelvic floor physical therapist,’ or ‘sex therapist’ using ‘find a provider’ websites from relevant professional societies.

28. Men: Get Cardiovascular Assessment for ED

Men experiencing erectile dysfunction should undergo a cardiovascular assessment, as ED can be a mirror to small vessel cardiovascular or cerebrovascular disease.