<p><a href="https://peterattiamd.com/ama38/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=220815-pod-ama38&utm_content=220815-pod-ama38-podfeed"> View the Show Notes Page for This Episode</a></p> <p><a href="https://peterattiamd.com/subscribe/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=220815-pod-ama38&utm_content=220815-pod-ama38-podfeed"> Become a Member to Receive Exclusive Content</a></p> <p><a href="https://peterattiamd.com/newsletter/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=220815-pod-ama38&utm_content=220815-pod-ama38-podfeed"> Sign Up to Receive Peter's Weekly Newsletter</a></p> <p>In this "Ask Me Anything" (AMA) episode, Peter dives deep into the question of whether there is such a thing as "too much exercise." He explores the theoretical "J-curve" relationship between exercise and longevity, whereby mortality risk declines with increasing activity levels only to see an uptick above a certain exercise volume threshold. While Peter maintains that exercise is perhaps the single most important tool we have to live longer and live better, he explains the challenges involved in identifying an optimal dose. He takes a hard look at studies—many of which have contradictory results—to highlight major limitations in methodology and how readers could be misled. Additionally, he discusses the rare, but real, risks associated with extreme levels of physical activity and concludes by weighing the benefits against the risks of exercise.</p> <p>If you're not a subscriber and listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your <a href="https://peterattiamd.com/members/private-podcast-feed/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=220815-pod-ama38&utm_content=220815-pod-ama38-podfeed">private RSS feed</a> or on our website at the <a href="http://peterattiamd.com/ama38/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=220815-pod-ama38&utm_content=220815-pod-ama38-podfeed">AMA #38 show notes page</a>. If you are not a subscriber, you can learn more about the subscriber benefits <a href="https://peterattiamd.com/subscribe/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=220815-pod-ama38&utm_content=220815-pod-ama38-podfeed">here</a>.</p> <p><strong>We discuss:</strong></p> <ul type="disc"> <li>How exercise reduces risk for all-cause mortality [2:40];</li> <li>Defining the metric called "MET" and how it's useful for evaluating different exercises [8:00];</li> <li>The challenge in determining the optimal exercise doses and the limitations of methods used to study the effect of exercise [13:45]; </li> <li>Using VO2 max as a proxy for fitness to better predict mortality risk [19:30];</li> <li>Reviewing data which support the theory of a "J-curve" relationship between exercise and longevity [25:00];</li> <li>Importance of understanding p-values and statistical significance [33:45];</li> <li>Deconstructing the studies that show a J-curve: major limitations and how one could be misled [37:00];</li> <li>Peter's takeaways on the theoretical "J-curve" relationship between exercise and longevity [51:30];</li> <li>Risk of sudden cardiac death from vigorous physical exertion [54:00];</li> <li>Atrial fibrillation associated with extreme levels of exercise [1:00:15];</li> <li>Parting thoughts: benefits of exercise far outweigh the risks [1:04:15]; and</li> <li>More.</li> </ul> <p>Connect With Peter on <a href="https://twitter.com/PeterAttiaMD">Twitter</a>, <a href="https://www.instagram.com/peterattiamd/">Instagram</a>, <a href="https://www.facebook.com/peterattiamd/">Facebook</a> and <a href="https://www.youtube.com/channel/UC8kGsMa0LygSX9nkBcBH1Sg">YouTube</a></p>
Actionable Insights
1. Prioritize Exercise for Longevity
Make time for exercise in your routine, as it is presented as the single most important tool to live longer and better, reducing mortality across all chronic diseases including ASCVD, cancer, type 2 diabetes, and Alzheimer’s disease.
2. Track Weekly Exercise Volume
Consider tracking your weekly MET-hours using a spreadsheet to account for both the duration and intensity of your activities, as this provides a normalized way to measure your total workload and evaluate research.
3. Consult Show Notes for Details
Refer to the podcast’s show notes for in-depth analysis of studies, mechanisms of exercise benefits, and specific MET values for various activities to deepen your understanding.
4. Become a Member for Content
Become a member at peteratiyahmd.com/subscribe to access complete AMA episodes, comprehensive show notes, private podcast feeds (Qualies), and discount codes for products.
5. Utilize Member Podcast Feed
If you are already a member, download the member-only podcast feed from peteratiyahmd.com/members to get full access to AMA episodes and avoid listening to sneak peeks.
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8. Review Disclosures
Visit peteratiyahmd.com/about to review Peter Attia’s up-to-date disclosures regarding conflicts of interest and companies he invests in or advises.