← The Peter Attia Drive

#205 - Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)

May 2, 2022 2h 55m 40 insights
<p class="p2"><span class="s1"><a href="https://peterattiamd.com/laynenorton2/?utm_source=podcast-feed&amp;utm_medium=referral&amp;utm_campaign=220502-pod-laynenorton&amp;utm_content=220502-pod-laynenorton-podfeed"> View the Show Notes Page for This Episode</a></span></p> <p class="p2"><span class="s1"><a href="https://peterattiamd.com/subscribe/?utm_source=podcast-feed&amp;utm_medium=referral&amp;utm_campaign=220502-pod-laynenorton&amp;utm_content=220502-pod-laynenorton-podfeed"> Become a Member to Receive Exclusive Content</a></span></p> <p class="p2"><span class="s1"><a href="https://peterattiamd.com/newsletter/?utm_source=podcast-feed&amp;utm_medium=referral&amp;utm_campaign=220502-pod-laynenorton&amp;utm_content=220502-pod-laynenorton-podfeed"> Sign Up to Receive Peter's Weekly Newsletter</a></span></p> <p class="p3">Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder, and <a href="https://peterattiamd.com/laynenorton/"><span class="s2">previous guest on <em>The Drive</em></span></a>. In the first half of this episode, Layne dives deep into the topic of energy balance, including the role that macronutrients and calories play in weight loss. He describes how many people struggle with tracking food and calories on their own across a variety of diets and how all of this can impact nutritional habits and behaviors. In the second half of the episode, Layne discusses the importance of protein and weightlifting for improving one's body composition and increasing muscle mass. He explains how he would prescribe different training and nutrition programs for two hypothetical clients—a 50-year-old female who is entering menopause and wants to improve her health, and a 40-to-50-year-old male who wants to maximize muscle mass. Additionally, Layne discusses a number of supplements that could potentially benefit a training program including whey protein, branch chain amino acids, creatine, nitric oxide boosters, and more.</p> <p class="p3">We discuss:</p> <ul class="ul1"> <li class="li3">Defining energy balance and the role of calories [2:30];</li> <li class="li3">Defining a calorie, whether they are all created equal, and how much energy you can extract from the food you eat [8:00];</li> <li class="li3">Factors influencing total daily energy expenditure [12:15]:</li> <li class="li3">The challenge of tracking energy expenditure accurately, and the thermic effect of different macronutrients [23:30];</li> <li class="li3">Challenges of sustained weight loss: metabolic adaptation, set points, and more [34:45];</li> <li class="li3">Weight loss strategies: tracking calories, cheat meals, snacks, fasting, exercise, and more [40:45];</li> <li class="li3">Sitting in discomfort, focusing on habits, and other lessons Layne learned as a natural bodybuilder [52:15];</li> <li class="li3">Commonalities in people who maintain long-term weight-loss [1:01:15];</li> <li class="li3">Does a ketogenic diet result in greater energy expenditure? [1:03:15];</li> <li class="li3">The metabolic benefits of exercise, muscle mass, and protein intake [1:15:00];</li> <li class="li3">The impact of lean muscle and strength on lifespan and healthspan [1:20:00];</li> <li class="li3">Hypothetical case study #1: Training program for 50-year-old female [1:27:45];</li> <li class="li3">Muscle protein synthesis in a trained athlete vs. untrained individual following a resistance training program [1:31:30];</li> <li class="li3">Protein and amino acids needed to build and maintain muscle mass [1:37:15];</li> <li class="li3">Nutrition plan for the hypothetical 50-year-old woman starting to build lean muscle [1:42:45];</li> <li class="li3">Dispelling myths that excess protein intake increases cancer risk through elevations in mTOR and IGF [1:55:30];</li> <li class="li3">Hypothetical case study #2: Training program for a 50-year-old, trained male wanting to increase muscle mass [2:04:00];</li> <li class="li3">Maximizing hypertrophy while minimizing fatigue—is it necessary to train to muscular failure? [2:11:30];</li> <li class="li3">Ideal sets and reps for the hypothetical 50-year-old male interested in hypertrophy [2:16:15];  </li> <li class="li3">Maximizing hypertrophy by working a muscle at a long muscle length [2:22:15];</li> <li class="li3">Recommended lower body exercise routines and tips about training frequency [2:24:00];</li> <li class="li3">Nutrition plan for the hypothetical 50-year old male wanting to add muscle [2:29:00];</li> <li class="li3">Cycling weight gain and weight loss when building lean muscle mass, and expectations for progress over time [2:33:30];</li> <li class="li3">Supplements to aid in hypertrophy training [2:38:30];</li> <li class="li3">More.</li> </ul> <p>Connect With Peter on <a href="https://twitter.com/PeterAttiaMD">Twitter</a>, <a href="https://www.instagram.com/peterattiamd/">Instagram</a>, <a href="https://www.facebook.com/peterattiamd/">Facebook</a> and <a href="https://www.youtube.com/channel/UC8kGsMa0LygSX9nkBcBH1Sg">YouTube</a></p>
Actionable Insights

1. Prioritize Lean Body Mass

Focus on building and maintaining lean body mass, as it is crucial for metabolic health and is inversely proportional to the risk of mortality after age 50. Strength, in particular, has a significant inverse correlation with all-cause mortality.

2. Commit to Resistance Training

Engage in resistance training at least three times a week for 30-40 minutes, as it significantly improves metabolic health, increases bone density, and contributes to a long, healthy life, regardless of age or starting fitness level.

3. Increase Protein Intake

Aim for a high protein intake, such as 1.6 to 2.4 grams per kilogram of body weight (e.g., 100-120g/day for a 135lb woman, or ~200g/day for a 180lb man), to maximize muscle protein synthesis and lean mass accrual.

4. Prioritize Overall Diet Quality

Focus on overall diet quality, including a high intake of fruits and vegetables, as this appears to be the most significant factor for health outcomes, rather than specific macronutrient ratios or isolated food types.

5. Choose Least Restrictive Diet

Select a dietary restriction method (e.g., calorie counting, carb restriction, time-restricted eating) that feels least restrictive to you as an individual, as adherence is the most critical factor for long-term success.

6. Sit with Discomfort

Practice sitting with discomfort, whether it’s hunger or other urges, and learn to distinguish true physical hunger from eating cues driven by stress, boredom, or societal factors.

7. Avoid Back-to-Back Mistakes

Adopt the rule of ’never do two bad things back to back’; if you miss a workout, ensure you work out the next day, and if you have a blowout meal, make the next meal a healthy one.

8. Track Food Intake Accurately

For one week, rigorously track every single piece of food consumed (no licks, bites, or snacks unaccounted for) to gain an accurate understanding of your actual energy intake, as self-estimation is often highly inaccurate.

9. Daily Consistent Weighing

Weigh yourself first thing in the morning, after using the bathroom and before eating, every single day, then average weekly weights to track progress accurately and account for daily fluid shifts.

10. Set Progressive Overload

To continue building muscle, consistently apply progressive overload by increasing the weight, repetitions, or number of sets over time, as adaptation requires continuous challenge.

11. Incorporate Training Tapers

Integrate planned recovery periods (tapers) into your training program to manage fatigue, allow for adaptation, and prevent overreaching, especially as you become more advanced or older.

12. Train Near Failure

Perform most resistance training sets at a Rate of Perceived Exertion (RPE) of 7-8 (3-2 reps shy of failure), occasionally pushing to 9 RPE (1 rep shy), as training close to failure provides similar hypertrophy stimulus with less recovery debt than training to absolute failure.

13. Optimize Set Volume

Aim for approximately 6-10 hard sets per muscle group per session for optimal hypertrophy, adjusting based on rest periods (e.g., 6 sets with 3+ minutes rest, 10 sets with 1-2 minutes rest).

14. Full Range of Motion

Ensure exercises are performed through a full range of motion, or at least emphasize the lengthened (stretched) position of the muscle, as this appears to be crucial for maximizing hypertrophy.

15. Utilize Machine Exercises

Incorporate machine-based exercises (e.g., hack squats, leg presses, pendulum squats) for major muscle groups, as they can provide effective stimulus with less fatigue and allow for a full range of motion, especially for those not prioritizing free weight strength.

16. Isolate with High Reps

For isolation exercises, use higher rep ranges (10-20 repetitions), shorter rest periods, and higher RPEs (8-9), potentially taking the last set to failure, to complement compound movements.

17. Aim for Slow Weight Gain

When aiming to gain muscle, pursue a very slow rate of weight gain (e.g., no more than 5 pounds over 12 weeks) with a slight caloric surplus of 100-200 calories above maintenance, to maximize lean mass accrual and minimize fat gain.

18. Focus on Calories & Protein

If feeling overwhelmed by tracking all macronutrients, prioritize tracking total calories and protein intake, as these two factors provide approximately 99% of the benefits for body composition goals.

19. Protein at Breakfast

Prioritize consuming a significant amount of protein at breakfast (e.g., 20-30 grams) to stimulate muscle protein synthesis early in the day, especially if your current breakfast is typically low in protein.

20. Leaner Meat Choices

To increase protein intake without significantly increasing calories, opt for leaner cuts of meat (e.g., sirloin, filet, chicken breast, venison) over fattier options like ribeye or T-bone.

21. Use Protein Shakes

Utilize protein shakes as a convenient and effective tool to boost protein intake, especially if you have a low appetite for solid protein or want to easily add protein to carb-heavy meals like cereal.

22. Ensure Adequate Fat Intake

Maintain a minimum fat intake of at least 20% of total calories or 40 grams per day to support hormone levels, as very low fat diets can potentially impair testosterone.

23. Customize Carb/Fat Ratio

After establishing protein and calorie targets, customize your carbohydrate and fat intake based on personal preference, adherence, and how your body responds (e.g., appetite, brain fog).

24. Whey Protein Benefits

Consider whey protein as a top-tier supplement due to its high content of leucine, branched-chain amino acids, and essential amino acids, making it highly bioavailable and effective for muscle protein synthesis.

25. Avoid Bad Protein Supplements

When choosing protein supplements, avoid brands that use proprietary blends or engage in ’nitrogen spiking’ (adding cheaper amino acids to artificially inflate protein content), as these practices can hide inferior product quality.

26. Creatine Monohydrate Only

Use creatine monohydrate for supplementation, as it is proven to saturate muscle cells 100% and is cost-effective; other forms of creatine are not superior and are often marketed to justify higher prices.

27. Creatine Loading or Maintenance

Choose between creatine loading (20g/day for 5-7 days) for faster saturation with potential GI discomfort, or a maintenance phase (5g/day) for slower saturation (3-4 weeks) with less discomfort, as both methods achieve full muscle saturation.

28. Take Creatine Daily

Consume creatine daily, even on non-training days, to maintain muscle saturation; if on a very tight budget, prioritize taking it on training days.

29. Boost Nitric Oxide

Consider supplementing with nitrates/nitrites (e.g., beetroot juice) or citrulline (6-8 grams per dose) to enhance exercise performance by increasing nitric oxide levels, with citrulline being more bioavailable than arginine.

30. Intra-Workout Nutrition Not Essential

Unless your workouts are exceptionally long (2-3+ hours) or you perform multiple training sessions per day, intra-workout nutrition (e.g., glucose/carbohydrates) is generally not necessary for most weightlifters or bodybuilders.

31. Understand Weight Fluctuations

Recognize that day-to-day weight changes are primarily due to fluid shifts, while weekly and monthly averages more accurately reflect changes in actual body mass.

32. Be Skeptical of Wearable Devices

Be cautious of calorie burn estimates from wrist-worn fitness devices, as studies show they can overestimate exercise energy expenditure by 28% to 93%.

33. Manage Alcohol Intake

Be mindful of alcohol consumption, as it is calorie-dense and can impair judgment, leading to poorer food choices.

34. Experience Acute Hunger

Consider a short water-only fast (3-5 days) at least once in your life to learn that acute hunger is manageable and comes in waves, building resilience against eating out of habit or boredom.

35. Understand Initial Training

Recognize that the first six weeks of resistance training primarily build tissue resilience and strength, with significant hypertrophy typically occurring after this initial adaptation phase.

36. Vary Rep Ranges

Incorporate a variety of rep ranges (e.g., <5 reps for some compound movements, 6-10 for others, 15-20 for isolation) into your training, as muscle growth can occur across a wide spectrum of repetitions, and variety can aid adherence.

37. Expect Fat Gain with Muscle

As an experienced lifter, accept that gaining muscle mass will likely involve some simultaneous fat gain, as the body prioritizes energy storage; focus on the long-term composition improvements.

38. Focus on Monthly Averages

During a muscle-gaining phase, monitor your progress by looking at monthly average weight trends rather than daily fluctuations, as weight gain often occurs in non-linear ‘chunks’.

39. Avoid BCAAs if Sufficient Protein

Branched-chain amino acid (BCAA) supplementation is generally not necessary if you are already consuming sufficient total daily protein from high-quality sources.

40. BCAAs for Plant-Based Diets

If following a plant-based diet and concerned about protein quality, consider adding supplemental BCAAs to meals or protein sources to enhance their anabolic potential.