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#104 Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep

Jul 11, 2025 3h 1m 28 insights
<p dir="ltr"><a href="https://www.foundmyfitness.com/aliquot?utm_campaign=ben_bikman_podcast&amp;utm_medium=podcast&amp;utm_source=podcast_description"> Get access to 130 episodes of my premium podcast, <strong>The</strong> <strong>Aliquot</strong>, as a FoundMyFitness Premium Member</a></p> <p dir="ltr">Insulin resistance silently shapes the trajectory of nearly every major chronic disease, yet it's often overlooked until blood sugar abnormalities become obvious. In this episode, <strong>Dr. Ben Bikman</strong> exposes the dietary culprits that drive metabolic dysfunction and highlights actionable, evidence-based tactics for improving metabolic health. Ben also addresses pressing questions about popular weight loss medications like Ozempic and other GLP-1 agonists: Are they groundbreaking solutions, or shortcuts with hidden metabolic consequences?</p> <p><strong>Timestamps:</strong></p> <ul> <li><strong>(0:00)</strong> Introduction</li> <li><strong>(4:51)</strong> Can you be insulin resistant with normal glucose levels?</li> <li><strong>(8:30)</strong> Can glucose monitors detect hidden insulin resistance?</li> <li><strong>(10:01)</strong> What your skin reveals about insulin resistance</li> <li><strong>(11:25)</strong> Why is insulin resistance behind so many chronic diseases?</li> <li><strong>(15:46)</strong> Does obesity cause insulin resistance—or vice versa?</li> <li><strong>(22:38)</strong> Insulin's surprising roles beyond blood sugar control</li> <li><strong>(23:36)</strong> What's driving weight gain—insulin or calories?</li> <li><strong>(30:30)</strong> Do saturated fats cause insulin resistance?</li> <li><strong>(37:02)</strong> Why refined carbs amplify risks from saturated fat</li> <li><strong>(40:04)</strong> Fructose vs. refined sugar—which spikes insulin more?</li> <li><strong>(41:01)</strong> High-carb vs. keto—which diet controls hunger better?</li> <li><strong>(45:27)</strong> Why low-carb diets might provide a metabolic advantage</li> <li><strong>(47:36)</strong> Does exercise give you metabolic 'wiggle room'?</li> <li><strong>(52:00)</strong> Why strength training beats cardio for insulin sensitivity</li> <li><strong>(54:03)</strong> Should you lower insulin before cutting calories?</li> <li><strong>(57:12)</strong> Does meal frequency drive insulin resistance?</li> <li><strong>(1:00:32)</strong> Is nighttime snacking giving you insomnia?</li> <li><strong>(1:02:24)</strong> Can a sugary breakfast lead to overeating later?</li> <li><strong>(1:07:19)</strong> Does late-night eating disrupt sleep more than blue light?</li> <li><strong>(1:08:59)</strong> Can one bad night's sleep trigger insulin resistance?</li> <li><strong>(1:12:23)</strong> Can air pollution cause weight gain?</li> <li><strong>(1:16:15)</strong> Vaping vs. smoking—which is worse for metabolic health?</li> <li><strong>(1:17:40)</strong> Can statins and antidepressants trigger weight gain?</li> <li><strong>(1:20:22)</strong> How to reverse insulin resistance in 90 days</li> <li><strong>(1:26:59)</strong> Does apple cider vinegar really lower blood sugar?</li> <li><strong>(1:30:54)</strong> Ketone supplements—are the metabolic benefits real?</li> <li><strong>(1:36:34)</strong> Why some ethnicities get diabetes without obesity</li> <li><strong>(1:44:28)</strong> How oversized fat cells trigger metabolic chaos</li> <li><strong>(1:49:28)</strong> Do seed oils silently promote insulin resistance?</li> <li><strong>(1:52:44)</strong> Seed oils—always harmful or only when heated?</li> <li><strong>(1:58:35)</strong> Fat, muscle, or liver—where does insulin resistance start?</li> <li><strong>(2:04:21)</strong> Do fat cells shrink or disappear with weight loss?</li> <li><strong>(2:07:05)</strong> Are shrunken fat cells still insulin resistant?</li> <li><strong>(2:08:15)</strong> Can exercise and cold therapy specifically shrink visceral fat?</li> <li><strong>(2:09:40)</strong> Injecting insulin for muscle—are the risks worth it?</li> <li><strong>(2:12:45)</strong> Are drugs like Ozempic a shortcut or solution for obesity?</li> <li><strong>(2:19:12)</strong> Are current GLP-1 agonist doses too high?</li> <li><strong>(2:20:02)</strong> Microdosing GLP-1 drugs—a solution for carb cravings?</li> <li><strong>(2:26:01)</strong> Do these medications cause muscle loss—or is it poor nutrition?</li> <li><strong>(2:28:30)</strong> Do GLP-1 agonist benefits extend beyond weight loss?</li> <li><strong>(2:30:41)</strong> Could these treatments actually promote longevity?</li> <li><strong>(2:36:12)</strong> The dark side of GLP-1 drugs—can they trigger depression?</li> <li><strong>(2:39:31)</strong> Insulin vs. glucose—what really drives accelerated aging?</li> <li><strong>(2:44:34)</strong> How high glucose levels damage cells—from glycolysis to sorbitol</li> <li><strong>(2:46:40)</strong> How insulin shuts down your body's stress defenses</li> <li><strong>(2:51:15)</strong> Which biomarkers best predict biological aging?</li> <li><strong>(2:55:05)</strong> One simple breakfast change to lower insulin</li> <li><strong>(2:57:19)</strong> Does eating dinner early improve insulin sensitivity?</li> </ul> <p><a href="https://www.foundmyfitness.com/episodes/ben-bikman?utm_campaign=ben_bikman_podcast&amp;utm_medium=podcast&amp;utm_source=podcast_description"> Show notes, transcript, and summary are available by clicking here</a></p> <p><a href="https://www.youtube.com/watch?v=gMyosH19G24">Watch this episode on YouTube</a></p>
Actionable Insights

1. Address Insulin Resistance as Root Cause

Recognize insulin resistance as a common origin for most chronic diseases, simplifying the approach to improving overall health and longevity by focusing on this core issue.

2. Measure Fasting Insulin Annually

Request a fasting insulin measurement as part of your annual blood tests, as it’s the earliest indicator of insulin resistance, often decades before glucose levels show a problem. Aim for levels below six micro units per mil for optimal metabolic health.

3. Control Carbs, Prioritize Protein, Fat

Adopt a dietary strategy to control carbohydrate intake by focusing on whole fruits and vegetables (mindful of sugary/starchy ones), prioritize protein, and consume natural fats accompanying protein sources without fear. This approach effectively lowers insulin and promotes fat burning.

4. Optimize Breakfast to Control Insulin

Change your breakfast habits to avoid early morning insulin spikes, which can disrupt metabolic flexibility. Either fast through breakfast (consuming only non-caloric drinks) or choose low glycemic load vegetables, berries, protein, and fat to extend the insulin-low state until lunch.

5. Prioritize Sleep to Prevent Insulin Resistance

Ensure adequate, quality sleep, as even one night of poor sleep significantly elevates stress hormones like cortisol and epinephrine, leading to acute insulin resistance. Good sleep is fundamental for maintaining metabolic health.

6. Build Muscle for Glucose Clearance

Engage in strength training to build and maintain muscle mass, as muscle is the body’s largest consumer of glucose. More muscle provides a significant metabolic buffer, helping to clear glucose from the bloodstream more efficiently and improving insulin sensitivity.

7. Control Insulin Before Calorie Restriction

Prioritize lowering insulin levels through dietary changes before strictly cutting calories for weight loss. This approach leverages metabolic advantages like increased metabolic rate and ketone excretion, making calorie reduction more sustainable and preventing rebound hunger.

8. Avoid High-Fat, High-Carb Combinations

Eliminate diets that combine high amounts of saturated fat with refined carbohydrates, as this combination is uniquely detrimental to metabolic health, promoting fat storage, insulin resistance, and adverse cardiovascular outcomes.

9. Eat Whole Foods, Avoid Processed

Focus on consuming whole, unprocessed foods and minimize items from bags and boxes with barcodes. This strategy naturally eliminates refined starches, sugars, and seed oils, which are primary drivers of insulin resistance.

10. Prioritize Strength Training to Failure

If time is limited for exercise, prioritize strength training and aim to reach muscle failure during your sets. This method offers superior improvements in insulin sensitivity compared to aerobic training for the same time investment.

11. Exercise After Meals to Blunt Glucose

Incorporate 10 to 15 minutes of physical activity, such as a walk, immediately after your largest or most carbohydrate-heavy meal. This ’exercise snack’ can significantly reduce post-meal glucose spikes and the associated insulin response.

12. Avoid Evening Snacking

Refrain from eating snacks in the evening, especially sugary ones, as going to bed with elevated blood sugar can activate the sympathetic nervous system and increase body temperature, leading to disrupted sleep and compounding metabolic issues.

13. Stop Eating Hours Before Bed

Aim for a minimum three to four-hour gap between your last meal and bedtime. This allows for complete digestion and prevents hyperglycemia and fullness from interfering with sleep quality and metabolic recovery.

14. Lower Insulin for Metabolic Advantage

Understand that maintaining low insulin levels promotes two key adaptations: a higher metabolic rate (burning 200-500 extra calories daily) and calorie excretion through ketones. These benefits provide ‘metabolic wiggle room’ to prevent fat storage and manage weight.

15. Target Visceral Fat with Epinephrine

To specifically reduce visceral fat, engage in activities that increase epinephrine, such as high-intensity interval training (HIIT) and deliberate cold exposure. Visceral fat cells are more responsive to these sympathetic nervous system activators.

16. Use Apple Cider Vinegar Before Meals

Consume a couple of tablespoons of apple cider vinegar diluted in water before your most starchy meal. Its acetic acid content helps reduce hepatic glucose production and stimulates AMPK, improving glucose uptake and lowering post-meal glucose curves.

17. Explore Exogenous Ketones

Consider supplementing with exogenous ketones to gain some benefits of ketosis, such as improved metabolic markers and appetite control, without strictly adhering to a ketogenic diet. This can be a viable approach for those seeking ketone benefits.

18. Check Skin for Insulin Resistance

Regularly inspect your skin, particularly around the neck and armpits, for signs like darkened, crinkled patches (acanthosis nigricans) or small skin tags. These are strong visual indicators of insulin resistance that can improve with lifestyle changes.

19. Monitor Post-Meal Glucose Response

Utilize a continuous glucose monitor (CGM) to track dynamic glucose changes after meals. If your glucose levels remain elevated for more than two hours after a carbohydrate-heavy meal, it suggests a potential problem with insulin sensitivity.

20. Eat Smart for Metabolic Health

Prioritize intelligent food choices to achieve and maintain leanness and overall metabolic soundness. A well-considered diet is generally more effective for long-term metabolic health improvements than exercise alone.

21. Front-Load Your Daily Calories

Structure your eating schedule to consume the majority of your calories earlier in the day, such as having a substantial breakfast and lunch. This meal timing strategy can lead to better metabolic outcomes and improved insulin sensitivity.

22. Low-Carb Allows More Saturated Fat

If you are consistently following a low-carbohydrate diet, you can generally consume more saturated fat without negatively impacting insulin resistance. This is due to altered metabolic pathways that reduce endogenous saturated fat production.

23. Prioritize Low Glycemic Carbs

Focus on consuming carbohydrates with a low glycemic load, such as cruciferous vegetables, berries, and citrus fruits, as they have minimal impact on insulin response. Individuals with type 2 diabetes should exercise caution with very sugary fruits.

24. Avoid Insulin Therapy for Type 2

For individuals with type 2 diabetes, be aware that insulin therapy, while lowering glucose, can paradoxically worsen overall metabolic health by increasing hyperinsulinemia, leading to more fat gain and higher risks of heart disease and cancer.

25. Microdose GLP-1s for Habit Change

If using GLP-1 agonists, discuss with your clinician a microdosing and cycling approach, framing the medication as a temporary aid to help rewire eating habits and control cravings, rather than a lifelong weight loss solution. The goal is to establish sustainable independent habits.

26. Consider Berberine for Insulin Sensitivity

Explore berberine supplementation as an effective way to improve insulin sensitivity.

27. Sustain Habits for Lasting Health

Recognize that any improvements in metabolic health achieved through lifestyle changes will only persist as long as those changes are maintained. Consistency and adherence to new habits are crucial for long-term benefits.

28. Manage Social Media Engagement

Be mindful of the time and energy invested in social media, as it can be a ‘black hole.’ Adopt a ’light touch’ approach to engagement to prevent it from negatively impacting other aspects of your life.