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#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

Nov 27, 2024 41m 53s 25 insights
<p><a href="https://www.foundmyfitness.com/aliquot?utm_campaign=protein_podcast&amp;utm_medium=podcast&amp;utm_source=podcast_description"> Discover my premium podcast, <strong>The Aliquot</strong></a></p> <p><a href="https://howtotrainguide.com/"><strong id="docs-internal-guid-80a6590d-7fff-7e57-5350-88250b1f7732">Download my "How to Train According to the Experts" guide</strong></a></p> <p>Protein is far more than a building block for muscle—it's essential for metabolic health, insulin sensitivity, and preventing conditions like type 2 diabetes and sarcopenia. But how much do we truly need? And could too much protein, especially from meat, actually be harmful? This episode challenges the conventional RDA of 0.8 g/kg, presenting research that supports higher intakes of 1.2–2 g/kg for maintaining muscle, improving body composition, and promoting longevity. We also confront myths around protein timing and the so-called "anabolic window." Lastly, we address concerns about protein's links to cancer, heart disease, and kidney function, showing how exercise can redirect growth factors like IGF-1 to promote repair while mitigating risks. </p> <p dir="ltr"><strong>Timestamps:</strong></p> <ul> <li><strong>(00:00)</strong> Download my "How to Train" guide</li> <li><strong>(00:51)</strong> Introduction</li> <li><strong>(03:32)</strong> Why muscle matters</li> <li><strong>(05:57)</strong> Why do we lose muscle?</li> <li><strong>(07:31)</strong> How to negate anabolic resistance</li> <li><strong>(08:24)</strong> Why it's never too late to build muscle</li> <li><strong>(09:05)</strong> Requirements for overweight & obese individuals</li> <li><strong>(09:52)</strong> Exposing the flaws of the RDA</li> <li><strong>(11:12)</strong> Optimal intake when resistance training</li> <li><strong>(11:55)</strong> What to do when losing weight</li> <li><strong>(13:08)</strong> Does protein harm healthy kidneys?</li> <li><strong>(14:59)</strong> How important is distribution?</li> <li><strong>(17:11)</strong> Debunking the "anabolic window"</li> <li><strong>(18:48)</strong> Benefits of pre-sleep intake</li> <li><strong>(20:20)</strong> Timing & distribution takeaways</li> <li><strong>(21:01)</strong> What are the best sources?</li> <li><strong>(24:05)</strong> Animal vs. plant protein</li> <li><strong>(26:27)</strong> Protein supplements (whey, casein, & collagen)</li> <li><strong>(27:57)</strong> Does high intake accelerate aging?</li> <li><strong>(31:32)</strong> Why exercise changes the story</li> <li><strong>(34:02)</strong> What we can learn from athletes</li> <li><strong>(34:36)</strong> Does high intake accelerate atherosclerosis?</li> <li><strong>(36:51)</strong> 8 key takeaways</li> </ul> <p><a href="https://www.foundmyfitness.com/episodes/protein?utm_campaign=protein_podcast&amp;utm_medium=podcast&amp;utm_source=podcast_description"> Show notes and transcript are available by clicking here</a></p> <p><a href="https://www.youtube.com/watch?v=fvO8e-2y37k">Watch this episode on YouTube</a></p>
Actionable Insights

1. Tailor Protein Intake to Goals

Adjust your daily protein intake based on your goals: 1.2-1.6 g/kg for general health, and 1.6 g/kg or more for older adults, athletes, or those aiming to lose weight while preserving lean mass. Always calculate based on ideal or lean body weight.

2. Resistance Training + Optimal Protein

Combine resistance training with a daily protein intake of 1.6 grams per kilogram body weight to significantly increase muscle mass and strength.

3. Combat Anabolic Resistance

Combat age-related anabolic resistance by combining regular physical activity with a higher daily protein intake, ideally around 1.6 grams per kilogram of body weight.

4. Prioritize Total Daily Protein Intake

Focus primarily on your total daily protein intake for optimizing muscle protein synthesis and training gains, as the ‘anabolic window’ is not as narrow as once thought, allowing flexibility in consuming protein before or after workouts.

5. Distribute Protein Evenly Across Meals

Ideally, distribute your protein intake evenly across 3-4 protein-rich meals, aiming for 20-25 grams per meal (20-30 grams for older adults), but remember that total daily protein intake remains the most crucial factor.

6. Higher Protein Dose for Older Adults

Older adults should consume higher doses of protein per meal (e.g., around 32 grams for an 80kg man) to maximally stimulate muscle protein synthesis, compensating for age-related anabolic resistance.

7. Pre-Sleep Protein for Muscle

Consume approximately 30 grams of protein before bed, particularly on resistance training days, to enhance overnight muscle protein synthesis, improve net protein balance, and aid muscle recovery and growth.

8. Increase Protein for Satiety/Weight Loss

Increase your protein intake to improve satiety, helping you feel fuller for longer and potentially preventing overeating, which is a major benefit for weight loss.

9. Preserve Muscle During Weight Loss

During weight loss, consume a higher protein diet to prevent the loss of lean body mass, ensuring that a greater proportion of weight lost is from fat.

10. Resistance Train During Weight Loss

When aiming for weight loss, combine a higher protein intake with resistance training to effectively prevent the loss of lean body mass.

11. Exercise for Lifelong Muscle

Engage in regular exercise, including strength training, both when young to build muscle reserve and in old age to slow and reverse age-related muscle and strength decline.

12. Combine Protein with Exercise

Combine higher protein intake with regular exercise, as physical activity positively influences how the body uses amino acids and growth factors, directing them beneficially towards muscle and brain health.

13. Optimize Plant-Based Protein

If following a plant-based diet, ensure adequate protein intake by consuming larger quantities of plant-based proteins, diversifying sources to create complete amino acid profiles, and incorporating plant-based protein isolates or concentrates.

14. Utilize Quality Protein Supplements

Utilize high-quality protein supplements like whey for rapid muscle protein synthesis (e.g., post-exercise) or casein for a prolonged amino acid release, offering targeted benefits even if dietary needs are met.

15. Target Leucine Per Meal

Aim to consume 20 grams of a high-quality protein, such as whey, per meal to provide 2-3 grams of leucine, which is a saturating dose to stimulate muscle protein synthesis for up to six hours.

16. Flexible Pre/Post-Workout Protein

Feel free to choose whether to consume protein before or after your workout, as there are no meaningful differences in outcomes, provided your total daily protein intake is sufficient.

17. Strength Train at Any Age

Engage in high-intensity strength training regardless of age, as studies show significant increases in muscle strength and size even in adults aged 90 and older.

18. Exercise to Redirect IGF-1

Engage in regular exercise to modulate growth factors like IGF-1, directing them towards muscle and brain tissue for repair and growth, while potentially reducing their pro-cancer effects elsewhere.

19. Calculate Protein by Ideal Weight

Calculate your daily protein needs based on your ideal or goal body weight, reflecting a healthy body fat percentage (e.g., 12-15% for men, 20% for women), to set realistic and effective targets.

20. Low-Calorie Pre-Sleep Shake

If you dislike going to bed hungry on training days, consider having a low-calorie protein shake before sleep, as it may enhance muscle gain.

21. Prioritize Whole Foods for Leucine

Prioritize consuming whole foods as the best strategy to ensure you are getting enough leucine, a critical amino acid for stimulating muscle protein synthesis.

22. Sprout/Ferment Plant Proteins

Sprout and ferment plant-based foods to improve the digestibility and absorption of plant protein, which can be lower due to fiber content.

23. Avoid Collagen for Muscle Building

Avoid using collagen as a primary protein source if your goal is to enhance skeletal muscle protein synthesis, as it has a suboptimal amino acid profile and does not significantly boost muscle growth.

24. High Protein Boosts Metabolism

Consume a high protein diet, as it may cause a slight increase in your metabolic rate due to the thermic effect of food, helping you burn more calories daily.

25. Download Free Training Guide

Download the free ‘How to Train According to the Experts’ guide at howtotrainguide.com to access comprehensive advice on training, nutrition, and supplementation from leading experts.