<div>In this episode, Rhonda describes NAD+ (perhaps one of the most important molecules in the human body), why it is so important for aging, and why it declines with age. </div> <div> </div> <div><strong>In this episode, you'll discover: </strong></div> <ul> <li><strong>(00:00)</strong> Introduction</li> <li><strong>(03:07)</strong> Overview of NAD+, a source of cellular energy</li> <li><strong>(09:18)</strong> NAD+ fuels PARP and sirtuin enzymes, promoting longevity</li> <li><strong>(12:37)</strong> How can I raise NAD+ levels?</li> <li><strong>(17:03)</strong> Can NAD+ boosters (NMN & NR) promote cancer growth?</li> <li><strong>(19:15)</strong> Making sense of the research so far</li> <li><strong>(27:03)</strong> Why not supplement with NAD+ directly?</li> <li><strong>(29:23)</strong> Clinical trials investigating nicotinamide riboside are promising</li> <li><strong>(32:42)</strong> Recap and concluding thoughts</li> </ul> <p>If you're interested in learning more, you can read the <a href="https://www.foundmyfitness.com/episodes/nad-nr-nmn">full show notes here</a>.</p> <p><span style="font-weight: 400;">Join over 300,000 people and get the latest distilled information straight to your inbox weekly:</span> <span style="font-weight: 400;"><a href="https://www.foundmyfitness.com/newsletter">https://www.foundmyfitness.com/newsletter</a></span></p> <p><span style="font-weight: 400;">Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more:</span> <a href="https://www.foundmyfitness.com/crowdsponsor"><span style="font-weight: 400;">https://www.foundmyfitness.com/crowdsponsor</span></a></p>
Actionable Insights
1. Boost NAD Through Lifestyle
Increase your NAD levels by engaging in exercise, fasting, or caloric restriction, as these activities cause energy stress which has been shown to raise NAD.
2. Increase NAD Through Diet
Incorporate foods rich in tryptophan (like salmon, spinach, and nuts) and niacin/vitamin B3 (such as lean meats, legumes, and veggies) into your diet, as these are sources from which NAD can be synthesized in the body.
3. Consider NAD Booster Supplements
You may consider supplementing with nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) to potentially raise NAD levels, though most promising data comes from very high doses in animal studies, and human efficacy and long-term safety are still under investigation.
4. Store NAD Boosters Properly
If you choose to use NAD booster supplements like NR or NMN, keep them cold and ensure they are sourced from manufacturers who store them properly to prevent breakdown into nicotinamide, which may reduce sirtuin activation.
5. Access Found My Fitness Topic Pages
Explore the free topic pages on the Found My Fitness website for deep dive overviews, illustrations, and citations on subjects like NAD, NR, NMN, sirtuins, and resveratrol, to answer further questions.
6. Support Found My Fitness Premium
Become a Found My Fitness premium member for $15 per month to gain access to exclusive content, early podcast access, genetic report updates, research summaries, Q&A sessions, and more, while supporting the podcast’s free resources.
7. Explore IV NAD Infusion
Consider exploring intravenous NAD infusion as a potential method to boost NAD levels, as animal studies suggest direct injection at high doses may be beneficial for the brain and heart, though human data is currently lacking.