Use methods like saunas, hot yoga, or hot baths to therapeutically boost core body temperature. This practice can induce a powerful antidepressant response, sensitize thermoregulatory cooling pathways, and strengthen anti-depression mechanisms for long-term resilience.
Engage in consistent aerobic and strength training exercise to significantly improve depression symptoms. Exercise activates beneficial anti-inflammatory responses, increases brain serotonin, and helps muscles clear neurotoxic kynurenine metabolites.
Incorporate fasting into your routine, such as a 24-hour fast, to powerfully reduce inflammation and elevate mood. Fasting downregulates inflammatory complexes and has shown significant mood-elevating and anti-depressant effects.
Regularly practice meditation to induce positive changes in brain structure and function, leading to profound mystical or transformative experiences. Even short-term consistent practice (e.g., eight weeks) can begin to show measurable brain alterations.
Ensure consistent bright light exposure during the day, ideally 30 minutes outdoors, to support mood and healthy circadian rhythms. This practice can lower cortisol response and help treat various depressive disorders, including non-seasonal depression.
Minimize light exposure, especially blue light, during evening hours to promote natural melatonin release and healthy sleep. A dark environment is crucial for maintaining proper circadian rhythms, which are often disrupted in modern life.
Consider implementing “The Wild Five” program, an online resource integrating exercise, diet, sleep, social connectivity, and mindfulness/meditation. This structured approach has shown striking improvements in well-being within 30 days.
Be aware that while antidepressants offer powerful short-term relief for many, they may foster long-term reliance and potentially increase vulnerability to relapse upon cessation. They might also hinder the development of enduring behavioral changes that lead to personal transformation.
Refrain from taking NSAIDs or high-dose antioxidant supplements (like alpha-tocopherol and vitamin C) immediately after exercise. These substances can suppress the beneficial inflammatory and oxidative responses crucial for muscle restructuring and insulin sensitivity.
Investigate the potential of psychedelic-occasioned mystical experiences, such as those induced by psilocybin, for profound and lasting antidepressant, anti-anxiety, and smoking cessation effects. These experiences, when guided, can lead to significant life transformation.
Consider long-distance running as a practice to induce powerful spiritual or transcendent states. Historically, many cultures have used intense running to achieve heightened states of awareness and well-being.
Utilize genetic data services, like 23andMe, to learn about specific polymorphisms in circadian genes (e.g., N-PAS2) that may be associated with conditions like bipolar disorder. This can offer insights into personal circadian sensitivities.
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