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#025 Dr. Satchin Panda on Time-Restricted Feeding and Its Effects on Obesity, Muscle Mass & Heart Health

Jun 30, 2016 1h 39m 10 insights
<p><span style="font-weight: 400;">Dr. Satchidananda (Satchin) Panda is a professor in the Regulatory Biology Laboratory at the Salk Institute for Biological Studies.</span></p> <p>In this video we discuss...</p> <ul> <li><strong>(00:00)</strong> Introduction</li> <li><strong>(06:42)</strong> Why humans developed an internal clock (i.e., the circadian rhythm)</li> <li><strong>(15:28)</strong> Light is necessary to regulate our circadian clock</li> <li><strong>(25:02)</strong> Morning bright light exposure lowers cortisol levels and lifts mood, but the indoors are dim</li> <li><strong>(30:25)</strong> Using light exposure to reset jet-lag and help shift workers stay healthy</li> <li><strong>(36:17)</strong> Eating is an important regulator of the body's peripheral circadian clocks</li> <li><strong>(40:44)</strong> Time-restricted feeding protects from the harmful effects of a Western diet</li> <li><strong>(48:30)</strong> Time-restricted feeding increases muscle mass while reducing fat mass</li> <li><strong>(51:03)</strong> Mice who fasted 15-16 hours-per-day gained muscle endurance due to changes in mitochondria</li> <li><strong>(54:43)</strong> What's the difference between intermittent fasting and time-restricted feeding?</li> <li><strong>(01:00:02)</strong> Melatonin makes us less insulin-sensitive in the evening </li> <li><strong>(01:05:56)</strong> Dr. Panda's time-restricted eating mobile app helps research participants track their food</li> <li><strong>(01:20:39)</strong> Time-restricted feeding improves heart health </li> <li><strong>(01:27:31)</strong> The gut microbiota also follow a circadian rhythm</li> <li><strong>(01:34:12)</strong> How to participate in Dr. Panda's research</li> </ul> <p><span style="font-weight: 400;">If you're interested in learning more, you can read the <a href="https://www.foundmyfitness.com/episodes/satchin-panda">full show notes here</a>.</span></p> <p><span style="font-weight: 400;">Join over 300,000 people and get the latest distilled information straight to your inbox weekly:</span> <span style="font-weight: 400;"><a href="https://www.foundmyfitness.com/newsletter">https://www.foundmyfitness.com/newsletter</a></span></p> <p><span style="font-weight: 400;">Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more:</span> <a href="https://www.foundmyfitness.com/crowdsponsor"><span style="font-weight: 400;">https://www.foundmyfitness.com/crowdsponsor</span></a></p>
Actionable Insights

1. Optimize Eating Window for Health

Restrict your daily food intake to an 8-12 hour window, starting from your first bite of non-water food or drink. This practice can lead to decreased fat mass, increased lean muscle, improved glucose tolerance, and protection from obesity and diabetes, while also naturally reducing calorie intake by curbing late-night snacking.

2. Get Morning Bright Light Exposure

Expose yourself to bright light (around 1,000 lux, potentially blue-shifted) for several minutes early in the morning, shortly after waking. This activates melanopsin to suppress melatonin, promoting alertness, resetting your master circadian clock, and helping to regulate cortisol levels, which can also reduce depression.

3. Avoid Evening Bright & Blue Light

Minimize exposure to bright or blue-shifted light in the evening, ideally by using red-shifted lights or blue light filtering apps on devices. This prevents sending incorrect signals to your brain, allowing melatonin to naturally build up for better sleep and avoiding inhibition of insulin secretion, which can negatively impact metabolism and weight loss.

4. Synchronize Eating with Daylight

Ensure your eating window is aligned with the daylight hours, as the timing of food intake directly tells your liver and other peripheral clocks when to activate metabolic processes. This synchronization optimizes metabolism and insulin sensitivity, which is crucial given that insulin sensitivity decreases later in the day.

5. Prioritize Consistent, Quality Sleep

Aim for a regular and consolidated sleep schedule by optimizing your light exposure and eating times. A well-regulated sleep-wake cycle is fundamental for the proper functioning of your master circadian clock and the synchronization of all organ systems, preventing desynchronization that can lead to chronic diseases.

6. Manage Jet Lag with Light & Food

When traveling across time zones, actively manage both your light exposure and the timing of your meals to help your body’s clocks reset. Both factors are critical for entraining your master and peripheral clocks to the new time zone, thereby minimizing the disruptive effects of jet lag.

7. Implement Shift Worker Lifestyle Strategies

If you are a shift worker, focus on strategic light and lifestyle management to counteract the health detriments of irregular schedules. Chronic circadian disruption from shift work is linked to metabolic disease, cancer, and accelerated aging, making light exposure and lifestyle adjustments vital for health and productivity.

8. Seek Sufficient Daytime Light

Avoid prolonged periods in dim indoor environments, as many lack the necessary 1,000 lux of light required to fully activate your circadian clock. Insufficient bright light during the day can confuse your body’s internal timing, leading to desynchronization and potentially affecting mood and overall health.

9. Consider Blue-Shifted Light for Alertness

Incorporate blue-shifted light into your environment during the first half of the day. This type of light can help you stay awake and alert, and may also contribute to reducing symptoms of depression.

10. Contribute to Circadian Rhythm Research

Participate in Dr. Panda’s crowdsourced research by downloading the MyCircadianClock app and consistently logging pictures of your food. This action helps advance scientific understanding of circadian rhythms and their impact on human health, while also providing you with personal data tracking.