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#013 How The Gut Microbiota Affects Our Health with Dr. Erica & Dr. Justin Sonnenburg

Sep 3, 2015 46m 58s 17 insights
<div class="collapsible-content"><strong><span class="text">Dr. Justin Sonnenburg</span></strong></div> <div class="collapsible-content"><span class="text">Dr. Justin Sonnenburg is an associate professor of microbiology and immunology at Stanford and Dr. Erica Sonnenburg is a senior research scientist in the Sonnenburg lab where they research many aspects the interaction between diet with the 100 trillion or so bacteria in the gut (specifically the colon) and how this impacts the health of the host (which in this case is a laboratory research mouse).</span></div> <div class="collapsible-content"> <p class="p1">In this episode, we discuss...<span class="Apple-converted-space"> </span></p> <ul> <li class="p1"><strong>(00:00)</strong> Introduction</li> <li class="p1"><strong>(02:50)</strong> What is the gut microbiota?</li> <li class="p1"><strong>(08:10)</strong> A lack of dietary fiber starves the gut microbiota</li> <li class="p1"><strong>(16:13)</strong> The close interplay of our gut and immune system</li> <li class="p1"><strong>(17:58)</strong> Connecting the dots between the gut, immune system, inflammation, and autoimmune diseases</li> <li class="p1"><strong>(20:45)</strong> A diet with a variety of fibers promotes microbiome diversity and health<span class="Apple-converted-space"> </span></li> <li class="p1"><strong>(25:30)</strong> Artificial sweeteners induce glucose intolerance by altering the gut microbiota</li> <li class="p1"><strong>(29:00)</strong> Individualized responses to repeated antibiotic perturbation</li> <li class="p1"><strong>(30:27)</strong> The risks of antibiotic overuse</li> <li class="p1"><strong>(32:10)</strong> Probiotics can support a healthy microbiota following antibiotics</li> <li class="p1"><strong>(38:05)</strong> Factors during birth and infancy that influence microbiome development</li> </ul> </div> <div class="collapsible-content"> <p><span style="font-weight: 400;">If you're interested in learning more, you can read the <a href="https://www.foundmyfitness.com/episodes/the-sonnenburgs">full show notes here</a>.</span></p> <p><span style="font-weight: 400;">Join over 300,000 people and get the latest distilled information straight to your inbox weekly:</span> <a href="https://www.foundmyfitness.com/newsletter"><span style="font-weight: 400;">https://www.foundmyfitness.com/newsletter</span></a></p> <span class="text"><span style="font-weight: 400;">Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more:</span> <a href="https://www.foundmyfitness.com/crowdsponsor"><span style="font-weight: 400;">https://www.foundmyfitness.com/crowdsponsor</span></a></span></div>
Actionable Insights

1. Increase Dietary Fiber Intake

Consume significantly more dietary fiber, aiming for 30-35 grams daily as recommended by the U.S. government, or even up to 100-150 grams like our ancestors, because fiber is key to feeding beneficial gut bacteria which produce compounds that regulate the immune system and prevent inflammation.

2. Diversify Fiber Sources

Eat many different types of complex carbohydrates found in dietary fiber to foster a rich and robust gut microbial community, as different microbes specialize in consuming various carbohydrates, leading to a more stable ecosystem.

3. Prioritize Whole, Unprocessed Foods

Avoid foods that come in wrappers or packages, as processed foods lack diverse dietary fiber and often contain problematic compounds like artificial sweeteners and emulsifiers that harm the gut microbiota and induce inflammation.

4. Avoid Unnecessary Antibiotics

Limit antibiotic use whenever possible, as these broad-spectrum drugs harm beneficial gut microbes, making it harder for the microbiota to recover and potentially leading to long-term health issues like autoimmune diseases.

5. Support Infant Gut Microbiome

Parents should be mindful of choices early in a child’s life, including method of birth (vaginal delivery is preferred) and feeding (breastfeeding over formula), as these factors profoundly dictate the initial microbial community that will largely remain throughout life.

6. Use Probiotics Post-Antibiotics

Consider using probiotics, either in supplement form or in fermented foods, after major perturbations like antibiotic courses, to help shorten the duration of associated issues like diarrhea and act as ‘placeholders’ while the microbiota recovers.

7. Choose Verified Probiotic Supplements

If taking probiotic supplements, ensure they come from a trusted company and look for independent verification symbols like USP, as the supplement market is unregulated and many products may not contain viable organisms or the stated species.

8. Personalize Probiotic Strategy

Take a personalized approach to probiotics and fermented foods, systematically testing what works well and is compatible with your system without causing problematic side effects, as the best options can vary between individuals.

9. Discuss Antibiotic Necessity

Have a conversation with your physician to let them know you don’t expect antibiotics every time you get sick and are comfortable with a ‘wait and see’ approach if appropriate, as this can often lead to avoiding unnecessary prescriptions.

10. Eat Seasonally for Diversity

Consume foods that are in season to naturally increase the diversity of fruits and vegetables in your diet over the year, which helps provide a diverse amount of complex carbohydrates for your gut microbes.

11. Mother’s Diet for Infant Health

Pregnant or pre-pregnant mothers should consume a diet high in dietary fiber and fermented foods to foster a healthy microbiota that can be passed on to their child, though this area requires more extensive study.

12. Read The Good Gut Book

Read ‘The Good Gut: Taking Control of Your Weight, Your Mood, and Your Long-Term Health’ by Drs. Justin and Erica Sonnenberg to gain broad scientific understanding and practical advice on how to positively impact your gut microbiota.

13. Follow The Good Gut Facebook

Follow facebook.com/thegoodgut to stay updated on interesting studies and information related to gut health posted a couple of times a week.

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16. Listen to Coribar Podcast

Check out the ‘Coribar, Micronutrients, Fiber, and Polyphenols in a Bar’ podcast with Dr. Mark Shigenaga on iTunes for more information on fiber and related topics.

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