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#004 Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients

Feb 12, 2015 43m 17s 17 insights
<p class="p1"><strong>Dr. Bruce Ames</strong></p> <p class="p1">In this podcast, Dr. Rhonda Patrick interviews her mentor, Dr. Bruce Ames, about his triage theory and other nutrition topics. Dr. Ames was the 23rd most-cited scientist between 1973 and 1984, which is evidence of his long and productive career investigating human health and disease. Dr. Ames continues his research expanding our knowledge of nutrients such as vitamin D and its role in Autism spectrum disorder.</p> <p class="p1">In this episode, we discuss...</p> <ul> <li class="p1"><strong>(00:00)</strong> Introduction</li> <li class="p1"><strong>(04:18)</strong> Dr. Ames discovers vitamin deficiency-induced DNA damage</li> <li class="p1"><strong>(10:35)</strong> Triage theory explains nutrient rationing<span class="Apple-converted-space"> </span></li> <li class="p1"><strong>(14:37)</strong> Nutrient deficiencies cause insidious damage and accelerate aging</li> <li class="p1"><strong>(25:25)</strong> Expanding the list of essential vitamins (e.g., lutein & zeaxanthin)<span class="Apple-converted-space"> </span></li> <li class="p1"><strong>(31:05)</strong> A Western diet pattern is mostly empty calories</li> <li class="p1"><strong>(36:46)</strong> Challenges running randomized double-blind clinical trials in nutrition</li> <li class="p1"><strong>(38:12)</strong> Nutrition is not the focus of our current healthcare system</li> <li class="p1"><strong>(42:15)</strong> Dr. Ames' philosophy about healthy and delicious foods</li> </ul> <p class="p1"><span style="font-weight: 400;">If you're interested in learning more, you can read the <a href="https://www.foundmyfitness.com/episodes/bruce-ames">full show notes here.</a></span></p> <p><span style="font-weight: 400;">Join over 300,000 people and get the latest distilled information on triage theory, longevity & micronutrients straight to your inbox weekly:</span> <a href="https://www.foundmyfitness.com/newsletter"><span style="font-weight: 400;">https://www.foundmyfitness.com/newsletter</span></a></p> <p class="p1"><br /> <span style="font-weight: 400;">Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more:</span> <a href="https://www.foundmyfitness.com/crowdsponsor"><span style="font-weight: 400;">https://www.foundmyfitness.com/crowdsponsor</span></a></p>
Actionable Insights

1. Understand Nutrient Triage Theory

Recognize that when nutrient intake is suboptimal, the body prioritizes essential short-term survival functions over long-term health processes like DNA repair, leading to insidious damage that contributes to diseases of aging.

2. Consider Long-Term Nutrient Deficiencies

Understand that a lack of acute deficiency symptoms (like scurvy or beriberi) does not mean you are getting enough vitamins and minerals to prevent long-term health consequences, which are often the diseases of aging.

3. Prioritize Diet Over Minor Radiation

Recognize that ‘bad diets’ causing folic acid deficiency can lead to chromosome breaks, similar to radiation, and are a more significant health concern than ‘incredibly tiny amounts’ of environmental radiation.

4. Adopt a Good, Varied Diet

Strive to eat a ‘wonderful diet’ like a Mediterranean diet, incorporating diverse, tasty foods such as fish and vegetables cooked with olive oil and garlic, as this can make you feel better and provide essential nutrients.

5. Consume Green Vegetables Regularly

Eat green vegetables like spinach or kale often to obtain essential nutrients such as vitamin K, magnesium (found in chlorophyll), and folic acid, which are crucial for preventing insidious damage and supporting long-term health.

6. Eat Fish for Omega-3s

Consume fish to obtain omega-3 fatty acids, which are critical for brain function and may play a role in conditions like autism, ADHD, and impulsive behavior.

7. Avoid Empty Calories

Recognize that Americans often consume ’empty calories,’ which contribute to widespread deficiencies in essential vitamins and minerals, and prioritize nutrient-dense foods instead.

8. Test Vitamin D Levels

Get your vitamin D levels tested, especially if you have dark skin or live in northern latitudes, as 90% of individuals with darker skin tones are often too low due to reduced UVB radiation absorption.

9. Supplement Vitamin D if Sun-Deprived

If you spend significant time indoors or have genetic reasons preventing sufficient vitamin D synthesis from sun exposure, ensure you take a vitamin D pill.

10. Consider a Multivitamin Supplement

View a multivitamin and mineral supplement as ‘good insurance’ to help ensure adequate intake of various micronutrients, especially if you’re not a biochemist tracking every nutrient.

11. Measure Nutrient Levels Personally

Do not rely solely on general population RDAs or studies that don’t account for individual deficiencies; instead, measure your own nutrient levels before and after interventions to ensure you reach sufficient ranges.

12. Consider Genetic Nutrient Needs

Be aware that genetic polymorphisms can influence your individual requirements for certain nutrients, such as magnesium or vitamin D, meaning you might need more than others.

13. Check Vitamin A Source in Supplements

Be aware that a significant portion of the population has a genetic polymorphism preventing efficient conversion of beta-carotene into active vitamin A (retinol), so check your multivitamin’s vitamin A source.

14. Consume Lutein and Zeaxanthin

Include foods rich in lutein and zeaxanthin in your diet, as these carotenoids are found in the macular of the eye and are essential for preventing macular degeneration.

15. Include Nuts in Diet

Incorporate nuts into your diet to gain beneficial nutrients.

16. Engage in Regular Exercise

Incorporate regular exercise into your routine, as exemplified by Dr. Ames working out twice a week with a personal trainer, to support long-term health and longevity.

17. Consult Reliable Nutrition Resources

Seek advice on micronutrients from reputable sources like the Linus Pauling Institute’s website to gain knowledge about proper intake.