2025
#108 The Best Type of Exercise for Longevity
#107 Why You Can't Sleep (and How to Fix It) | Dr. Michael Grandner
#106 How To Increase Your Testosterone Levels Naturally | Derek from MPMD
#105 Exogenous ketones, my coffee protocol, and supplements for blood sugar regulation (Premium Member Q&A July 2025)
#104 Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep
#103 A Deep Dive on Using Coffee For Health & Longevity (Full Guide & Research)
#102 Why Vitamin D Deficiency Accelerates Brain Aging
#101 Dr. Andy Galpin: The Optimal Diet, Supplement, & Recovery Protocol for Peak Performance
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD
#099 The Science of Exercise for Cancer | Kerry Courneya, PhD
#098 How to Train According to the Experts
2024
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep
#095 What Microplastics Are Doing to Your Brain, Body, and Reproductive Systems
#094 Dr. Layne Norton on Building Muscle – Insights on Diet, Training, and Supplements
#093 Dr. Luc van Loon: Optimizing Protein Intake & Distribution for Muscle Growth
#092 The Truth About Alcohol: Risks, Benefits, and Everything In-Between | Dr. Rhonda Patrick
#091 Andrew Huberman, PhD: How to Improve Motivation & Focus By Leveraging Dopamine
#090 How Exercise Prevents & Reverses Heart Aging | Benjamin Levine, M.D.
#089 Why Exercise Intensity Matters for Longevity | CrossFit for Health 2024
#088 The Science of Optimizing Sleep - Special Preview
#087 The Science of Magnesium and Its Role in Aging and Disease | Dr. Rhonda Patrick
#086 How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick
2023
#085 Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging
#084 The Longevity & Brain Benefits of Vigorous Exercise | Dr. Rhonda Patrick
#083 How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick
#082 The Science of Vigorous Exercise — Should We Train Hard or Train Long? | Martin Gibala, Ph.D.
#081 The Anabolic Potential of Omega-3 Fatty Acids | Chris McGlory, PhD
#080 How Heat Therapy Improves Slow Wave Sleep
#079 Blood-Brain Barrier Dysfunction in Alzheimer's Disease and Dementia | Axel Montagne, Ph.D.
2022
#078 Resistance training for time efficiency, body composition, and maximum hypertrophy | Brad Schoenfeld, Ph.D.
#077 Rewriting genomes to eradicate disease and aging | Dr. George Church
#076 Building Muscle with Resistance Exercise and Reassessing Protein Intake | Stuart Phillips, PhD
#075 Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction & Metabolic Disorder
#074 Dr. Dominic D'Agostino on Developing a Well-Designed Ketogenic Diet and Harnessing Its Benefits
#073 Sauna Benefits Deep Dive and Optimal Use with Dr. Rhonda Patrick & MedCram
#072 Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace?
#071 Peter Diamandis, MD, and Tony Robbins on strategies that promote longevity now – and in the very near future
#070 Dr. Eran Elinav on Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut
2021
#069 COVID Vaccine Myths, Questions, and Rumors with Rhonda Patrick and Roger Seheult
#068 Dr. Bill Harris on the Omega-3 Index: Increasing Omega-3 to Promote Longevity & Transform Health
#067 Dr. Ashley Mason on Drug-free Approaches for Treating Depression, Insomnia, and Overeating
#066 Dr. Mark Mattson on the Benefits of Stress, Metabolic Switching, Fasting, and Hormesis
#065 Dr. Satchin Panda on Circadian Insights into Exercise Timing, Melatonin Biology, and Peak Cognition
#064 Dr. Michael Snyder on Continuous Glucose Monitoring and Deep Profiling for Personalized Medicine
#063 Dr. Roger Seheult from MedCram on COVID-19 Vaccines, Vitamin D, and Heat Hydrotherapy
2020
#062 Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks
#061 Q&A with Dr. Jed Fahey on Sulforaphane, Moringa and Chemoprotection
#060 Dr. Giselle Petzinger on Exercise for Parkinson's Disease
#059 Aliquot #3: Q&A Mashup - Fasting
#058 Aliquot #2: Q&A Mashup - Sauna
#057 Aliquot #1: Q&A Mashup - Pregnancy and child development
#056 The Biology of Breast Milk
#055 COVID-19 Q&A #2 - Antibody-Dependent Enhancement, Cross-Immunity, Immunity Duration & More
#054 Vitamin C: Oral vs. Intravenous, Immune Effects, Cancer, Exercise Adaptation & More
#053 COVID-19 Q&A #1 with Rhonda Patrick, Ph.D.
#052 New Omega-3, sulforaphane research, and more! [Kevin Rose Show]
2019
#051 Is Resveratrol a Longevity Compound?
#050 NAD+ in Aging: Role of Nicotinamide Riboside and Nicotinamide Mononucleotide
#049 Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More
#048 Sauna Use as an Exercise Mimetic for Heart and Healthspan
#047 Exercise as a Treatment for Depression
#046 Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging
#045 Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System
#044 Fasting Q&A with Dr. Rhonda Patrick and Mike Maser
2018
#043 Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease
#042 Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD
#041 Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia
2017
#040 Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors
#039 Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies
#038 Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation
#037 Dr. Jari Laukkanen on Sauna Use for the Prevention of Cardiovascular & Alzheimer's Disease
#036 Judith Campisi, Ph.D. on Cellular Senescence, Mitochondrial Dysfunction, Cancer & Aging
#035 Gordon Lithgow, Ph.D. on Protein Aggregation, Iron Overload & the Search for Longevity Compounds
#034 Refined Sugar and Its Effects on Mortality, the Brain, Cancer, Hormones & More
#033 Does Saturated Fat Cause Heart Disease?
#032 Does Meat Consumption Cause Cancer?
#031 On Depression and Its Underlying Causes
#030 Roland Griffiths, Ph.D. on Psilocybin, Psychedelic Therapies & Mystical Experiences
#029 Jed Fahey, Sc.D. on Isothiocyanates, the Nrf2 Pathway, Moringa & Sulforaphane Supplementation
2016
#028 Sulforaphane and Its Effects on Cancer, Mortality, Aging, Brain and Behavior, Heart Disease & More
#027 Valter Longo, Ph.D. on the Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis
#026 Ruth Patterson, Ph.D. on Time-Restricted Eating in Humans & Breast Cancer Prevention
#025 Dr. Satchin Panda on Time-Restricted Feeding and Its Effects on Obesity, Muscle Mass & Heart Health
#024 Ray Cronise on Cold Thermogenesis, Intermittent Fasting, Weight Loss & Healthspan
#023 Dominic D'Agostino, Ph.D. on Modified Atkins Diet, Ketosis, Supplemental Ketones and More
#022 Peter Attia, M.D. on Macronutrient Thresholds for Longevity & Performance, Cancer & More
#021 How Cryotherapy Affects the Brain, the Immune System, Metabolism, and Athletic Performance
#020 Rich Roll on Self-Transformation, Environmental Impact of Food, and the Plant-Based Diet
2015
#019 Dr. Darya and Kevin Rose Talk Meditation Retreats, Diet, Seasonal Eating, and More
#018 Dr. Pierre Capel on the Power of the Mind & the Science of Wim Hof
#017 Wim Hof (the Iceman) on Defeating Extreme Cold & Attenuating the Immune Response
#016 PRESENTATION: Rhonda Speaks at the Orthomolecular Congress in Bussum, Netherlands
#015 Buffering the Negative Effects of Chronic Stress with Meditation
#014 Sauna Use and Building Resilience to Stress with Dr. Rhonda Patrick
#013 How The Gut Microbiota Affects Our Health with Dr. Erica & Dr. Justin Sonnenburg
#012 Dr. Ronald Krauss on LDL Cholesterol, Particle Size, Heart Disease & Atherogenic Dyslipidemia
#011 CHORIBar: Micronutrients, Fiber & Polyphenols in a Bar
#010 Dr. Aubrey de Grey and Dr. Rhonda Patrick Talk Aging
#009 Rhonda Answers the Most Popular Questions About Vitamin D
#008 Sleep, Daylight Anchoring, and Effects on Memory & Obesity with Dan Pardi
#007 Tim Ferriss on Biomarkers, Ketosis, Microbiome, and Lyme Disease
#006 Jim Kean Talks Biomarkers, Building a Spectator Sport
#005 Dr. Bruce Ames Talks CHORI-Bar Weight Loss
#004 Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients