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Should You Be Taking Psychedelics? The Benefits, the Risks, and the Science. | Jay Michaelson

Feb 24, 2025 1h 20m 21 insights
<p>Featuring a meditation teacher, author, professor, and dedicated experimenter with these molecules.</p> <p> </p> <p>Jay Michaelson is a journalist, meditation teacher, rabbi, and professor of religious studies whose work for the last several years has been focused on psychedelics, meditation, and spirituality.</p> <p>Jay is a field scholar at Emory University's Center for Psychedelics and Spirituality, and a fellow at Harvard Law School's project on Psychedelic Use, Law, and Spiritual Experience. He is currently a visiting professor at Harvard Law School, teaching courses on psychedelics, law, and religion.</p> <p> </p> <p><strong>In this episode we talk about:</strong></p> <ul> <li>Everything you should know about psychedelics if you're wondering whether to give them a try</li> <li>What the research shows thus far</li> <li>The differences among various compounds</li> <li>The overlap between meditation and psychedelics</li> <li>The difference between spirituality and healing</li> <li>The dizzying question of whether these medicines have a separate consciousness </li> <li>And more</li> </ul> <p> </p> <p><strong>Related Episodes:</strong></p> <ul> <li><a href="https://www.danharris.com/p/psychedelics-and-meditation-michael-08f" rel="noopener noreferrer" target="_blank">Psychedelics and Meditation | Michael Pollan - by DB - Dan Harris</a></li> <li><a href="https://www.danharris.com/p/what-to-do-about-eco-anxiety-jay-9f3" rel="noopener noreferrer" target="_blank">What to do About Eco-Anxiety | Jay Michaelson</a></li> </ul> <p> </p> <p><strong>Follow Dan on social:</strong> <a href="https://bit.ly/3tGigG5" rel="noopener noreferrer" target="_blank"><strong>Instagram</strong></a><strong>,</strong> <a href="https://bit.ly/3FOA84J" rel="noopener noreferrer" target="_blank"><strong>TikTok</strong></a></p> <p><strong>Subscribe to our</strong> <a href="https://bit.ly/3FybRzD" rel="noopener noreferrer" target="_blank"><strong>YouTube Channel</strong></a></p> <p><strong>Our favorite playlists on:</strong> <a href="https://spoti.fi/3Qa8kMT" rel="noopener noreferrer" target="_blank"><strong>Anxiety</strong></a><strong>,</strong> <a href="https://spoti.fi/3MjtMxF" rel="noopener noreferrer" target="_blank"><strong>Sleep</strong></a><strong>,</strong> <a href="https://spoti.fi/3QvyA5J" rel="noopener noreferrer" target="_blank"><strong>Relationships</strong></a><strong>,</strong> <a href="https://spoti.fi/3QxZASc" rel="noopener noreferrer" target="_blank"><strong>Most Popular Episodes</strong></a></p> <p> </p> <p><strong>Additional Resources:</strong></p> <ul> <li><a href="https://jaymichaelson.substack.com/" rel="noopener noreferrer" target="_blank">Both/And with Jay Michaelson</a></li> <li><a href="https://www.danharris.com/s/meditations" rel="noopener noreferrer" target="_blank">A special guided meditation from Jay to accompany this episode </a></li> <li>Two free upcoming events:</li> <li><a href="https://psychedelics.emory.edu/events/sos-twenty-five.html" rel="noopener noreferrer" target="_blank">Emory Science on Spiritual Health Conference</a> (free, online) </li> <li><a href="https://pjil.law.harvard.edu/annualconferences/" rel="noopener noreferrer" target="_blank">Harvard Symposium on Psychedelics in Monotheistic Traditions (which Jay co-chairing)</a></li> </ul> <p> </p>
Actionable Insights

1. Prioritize Safety & Guidance

Recognize that psychedelics carry a significantly higher potential for harm than meditation, making proper guidance and screening essential before engaging with them. Do not enter without proper guidance or screening.

2. Ensure Proper Screening & Setting

A responsible guide or practitioner will screen participants for conditions like anxiety or panic disorder and choose an appropriate physical setting and medicine dosage to mitigate risks. Ensure the physical setting is safe and supportive, like a cozy living room, not an enclosed space.

3. Cultivate a Prepared Mindset

Before a psychedelic experience, cultivate an open mindset rather than approaching it with fear or resistance, as your mental state significantly influences the experience. A mindset of desperation to heal can also be a powerful asset.

4. Develop a Meditation Practice

Cultivate a meditation or yoga practice, as the ability to let go and be with difficult experiences without freaking out is incredibly valuable during higher-dose psychedelic journeys. This practice provides essential tools for navigating intense states.

5. Prioritize Post-Experience Integration

Understand that the integration period after a psychedelic experience is as crucial as the experience itself for lasting benefit. Dedicate time to process, review, and reflect on the experience, ideally with support, rather than immediately returning to daily routines.

6. Clarify Your Intention

Before considering psychedelics, clearly define your intention, whether it’s for exploration, spiritual growth, or addressing a specific mental health condition. This clarity will help guide your choices regarding medicine and approach.

7. Do Not Go It Alone

Involve a trusted person, such as a psychiatrist, therapist, or another reliable individual, in your psychedelic process. Do not attempt to navigate these experiences by yourself.

8. Thoroughly Research & Consult

Conduct extensive reading and research on psychedelics, including books and experiences, and consult mental health professionals and meditation teachers you trust for advice and potential referrals. Be discerning about who you listen to.

9. Choose a Trustworthy Guide

Select a guide or therapist whose worldview aligns with yours and whom you deeply trust, especially when in a vulnerable state. Your sense of trust in the guide is paramount, regardless of their specific beliefs.

10. Start Small with Dosing

If you have reservations or are new to psychedelics, consider starting with microdosing or low doses under therapeutic guidance to gradually build confidence and acclimate to the experience.

11. Discuss Boundaries for Touch

Before an experience, proactively discuss and establish clear boundaries with your facilitator or guide regarding physical touch, as you may not be able to consent in the moment.

12. Practice Non-Resistance

During a psychedelic experience, especially a challenging one, practice non-resistance by letting go and floating downstream, as fighting the experience can contribute to a ‘bad trip’.

13. Listen to Your Intuition

Pay attention to your gut feelings about different psychedelic experiences; if a description excites you, explore it, but if it evokes strong reluctance or fear, listen to that intuition and proceed with caution or reconsider.

14. Exercise Caution in Early Field

Be aware that the psychedelic field is still in its early stages of development, akin to a ‘Wild West’ phase, meaning there’s a mix of quality and motives among practitioners, so exercise buyer beware.

15. Verify Self-Sourced Substances

If you choose to obtain substances independently, ensure you are very certain of the source and test them if possible, as current regulations make transparency difficult.

16. Consider MDMA for Softer Experiences

For those seeking a less intense or ‘softer’ psychedelic experience, MDMA is often described as showing ’love’ and having lower odds of a difficult experience compared to compounds like LSD or psilocybin.

17. Be Aware of Ketamine Risks

While legally accessible in many places, be mindful that ketamine carries an addictive capacity and overdose risk, unlike MDMA, and can be taken daily.

18. Don’t Feel Pressured to Use

Understand that you do not have to use psychedelics to be a committed, growth-oriented, or spiritual person, and you can achieve personal improvement or spiritual goals through other means.

19. Avoid Self-Criticism

Do not use the topic of psychedelics as another reason to engage in self-criticism, whether you choose to explore them or not.

20. Access App Guided Meditations

Download the ‘10% with Dan Harris’ app for a library of guided meditations to help with stress, anxiety, sleep, focus, and self-compassion, along with access to live community sessions and ad-free podcast episodes. A 14-day trial is available.

21. Utilize Subscriber Resources

If you are a paid subscriber at danharris.com, access the cheat sheet with key takeaways and a special guided meditation from Jay Michelson to help integrate the episode’s learnings.