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Chronic Stress Ages You. Here's How To De-Stress for Longevity. | Elissa Epel

Sep 1, 2025 1h 11m 26 insights
<p dir="ltr">How to reduce negative thoughts, get deep rest, and improve cellular health.</p> <p dir="ltr"> </p> <p dir="ltr"><a href="https://www.elissaepel.com/">Elissa Epel, Ph.D.</a>, is an international expert on stress, well-being, and optimal aging and a best-selling author of <a href="https://www.amazon.com/Telomere-Effect-Revolutionary-Approach-Healthier/dp/1455587974"> The Telomere Effect</a>, and <a href="https://www.amazon.com/Stress-Prescription-Seven-Days-More/dp/014313664X/ref=tmm_pap_swatch_0?_encoding=UTF8&amp;dib_tag=AUTHOR&amp;dib=eyJ2IjoiMSJ9.bTiNVG88CU_tDRZWy9esL9Gs7FKQBraGh-Vq-CxZR6dFtqMbp8lrp_Bv2-NljPcfE3sNoBCrP7q1mJ9oZ6W_NgW5bAvuoQPgv1mTG-ULjZOGpPhqUUw4e-L2FgmIUkO_XWLMESgcshDsu40wkYI3_2dr3clzjqBhJn8plwekSyk.GTPHRdV5qNmGVkWkADb0UTYfwonKVvgHO79H73_5yl0"> The Stress Prescription</a>. She is a Professor in the Department of Psychiatry & Behavioral Sciences, at the University of California, San Francisco, where she is Vice Chair of Psychology and directs the <a href="https://amecenter.ucsf.edu/">Aging Metabolism Emotions Center</a>. </p> <p><strong> </strong></p> <p dir="ltr">In this episode we talk about:</p> <ul> <li dir="ltr">What telomeres are</li> <li dir="ltr">Why chronic stress  accelerates our rate of aging – and how to reverse it</li> <li dir="ltr"> How we have way more control over aging than we think</li> <li dir="ltr">Small, consistent lifestyle changes we can make to promote longer telomeres </li> <li dir="ltr">The role of existential stress</li> <li dir="ltr">Meditation retreats as a reset for the nervous system</li> <li dir="ltr">How even 5-minutes of daily meditation can help</li> <li dir="ltr">Breathing practices that increase vagal tone </li> <li dir="ltr">Deep rest, and other states of mind that are crucial for cellular repair and growth </li> <li dir="ltr">How to counteract the impacts of stress eating </li> <li dir="ltr">How to reframe stress as a challenge</li> <li dir="ltr">And much more</li> </ul> <p><strong><br /> <br /></strong></p> <p dir="ltr">Related Episodes:</p> <ul> <li dir="ltr"><a href="https://www.danharris.com/p/become-an-active-operator-of-your-c16?utm_source=publication-search"> Become an Active Operator of Your Nervous System | Deb Dana</a></li> <li dir="ltr"><a href="https://www.danharris.com/p/what-science-and-buddhism-say-about-98d?utm_source=publication-search"> What Science and Buddhism Say About How to Regulate Your Own Nervous System | Deb Dana & Kaira Jewel Lingo</a></li> </ul> <p><strong><br /> <br /></strong></p> <p dir="ltr">Join Dan's online community <a href="http://www.danharris.com/">here</a></p> <p dir="ltr">Follow Dan on social: <a href="https://bit.ly/3tGigG5">Instagram</a>, <a href="https://bit.ly/3FOA84J">TikTok</a></p> <p dir="ltr">Subscribe to our <a href="https://bit.ly/3FybRzD">YouTube Channel</a></p> <p><strong><br /> <br /></strong></p> <p dir="ltr">On Sunday, September 21st from 1-5pm ET, join Dan and Leslie Booker at the New York Insight Meditation Center in NYC as they lead a workshop titled, "Heavily Meditated – The Dharma of Depression + Anxiety." This event is both in-person and online. Sign up <a href="https://www.nyimc.org/event/heavily-meditated/">here</a>! </p> <p><strong> </strong></p> <p dir="ltr">Get ready for another Meditation Party at Omega Institute! This in-person workshop brings together Dan with his friends and meditation teachers, Sebene Selassie, Jeff Warren, and for the first time, Ofosu Jones-Quartey. The event runs October 24th-26th. Sign up and learn more <a href="http://eomega.org/workshops/meditation-party-2025">here</a>!</p> <p><strong> </strong></p> <p dir="ltr">To advertise on the show, contact sales@advertisecast.com or visit <a href="https://advertising.libsyn.com/10HappierwithDanHarris">https://advertising.libsyn.com/10HappierwithDanHarris</a></p> <p> </p> <p>
Actionable Insights

1. Prioritize Deep Rest

Actively seek “deep rest” (blue mind) states, which involve releasing and letting go of control, through practices like meditation, Yoga Nidra, sound baths, Shavasana, or immersive music experiences, as this is crucial for cellular restoration.

2. Reframe Stress as Challenge

When facing stress, shift your mindset from threat to challenge by focusing on your resources, viewing the stress response as energizing, and telling yourself your body is preparing you to do well. This can lead to better problem-solving and clearer thinking.

3. Practice Slow Breathing

Engage in slow breathing practices, aiming for roughly six breaths per minute or less, to directly increase vagal tone, promote feelings of ease and joy, and shift your nervous system activity within minutes.

4. Daily Meditation for Well-being

Engage in at least five minutes of daily meditation to improve emotional well-being, reduce stress, lower depression and burnout, and increase enjoyment and purpose at work. These effects can last for months.

5. Control What You Can

Engage in practices like a “stress inventory” to identify what you can control versus what you cannot. Focus your energy on controllable aspects and consciously release the burden of uncontrollable situations.

6. Start, End Day with Joy

Shift focus from stress management to cultivating joy and positive emotions by starting and ending each day with practices like gratitude, anticipating positive opportunities, or reflecting on social connections, which builds stress resilience.

7. Attend Meditation Retreat

Consider attending a meditation retreat (even 1-3 days, or longer if possible) to recalibrate your nervous system, change your mental filter, and learn skills to enter restorative mode more easily. Scholarships and shorter options are available.

8. Break Up Chronic Stress

Implement short practices throughout the day to interrupt chronic stress, which can be defined as rumination or not feeling safe in the present, and prevent it from accumulating.

9. Go to Bed Earlier

Prioritize going to bed earlier to maximize the chances of getting more slow-wave sleep (deep sleep), which is the most restorative state for the body and mind, and when vagal tone is highest.

10. Increase Fruit, Vegetable Intake

Consistently eat more fruits and vegetables daily, as this small, cumulative change can lead to longer telomeres and contribute to healthy aging over decades.

11. Counteract Stress Eating

When feeling stressed and tempted to eat comfort foods like simple carbs, be aware that this can lead to dramatic glucose peaks and insulin resistance. Instead, ask yourself “How do I want to feel right now?” to make a more conscious food choice.

12. Set Low Bar for Habits

To establish long-term habits, set the bar very low for daily practices, focusing on quick, achievable wins that accumulate over time, rather cleaner than aiming for overly ambitious goals that are hard to maintain.

13. Develop Stress Shields

Create personal “stress shields” by cultivating specific thoughts about your resources, how you will perform, and how you view the stress response (e.g., “This is my body getting prepared to act”). These thoughts can shape your stress response into a positive challenge.

14. Create Personal Stress Mantra

Develop a personal mantra or statement that resonates with you (e.g., “I’m not nervous, I’m excited”) to use before and during stressful moments, helping to reframe your physiological response as an energizing challenge.

15. Visualize Releasing Burdens

When faced with an uncontrollable burden or worry, close your eyes and visualize yourself physically taking off a heavy backpack or putting down a brick, accompanied by big sighs, to practice releasing the mental weight.

16. Practice Drop the Rope

Visualize a difficult, uncontrollable situation as a boulder you’re pulling on with a rope. Practice opening your hands and dropping the rope to symbolize letting go of the struggle and useless problem-solving, even if the pain or worry remains.

17. Create Your Own Retreat

If formal retreats are not feasible, create your own retreat experience by spending time in nature or dedicating half-days or weekends to restorative practices, aiming for at least three days for a deeper reset if possible.

18. Take Daily Short Breaks

Integrate daily short breaks into your routine to reduce the “stress soup” and promote a rejuvenative and restorative environment for your cells.

19. Practice Morning Slow Breathing

Make slow breathing a morning habit to start the day with increased vagal tone and a settled nervous system, noticing and savoring the immediate benefits.

20. Use Straw Breathing Technique

Practice “straw breathing” by taking a deep inhale through the nose and a super slow exhale through pursed lips as if blowing through a straw. Use this for a couple of minutes before meditation or whenever feeling overwhelmed to settle down.

21. Combine Breathing with Exercise

For beginners, integrate somatic breathing practices after physical activities like pushups or exercise to help settle the body and mind, making it easier to feel the body and sit still for meditation.

22. Choose Your Mind State

When in a “yellow mind” state (chronic vigilance/cognitive load), consciously decide whether to upregulate to a positive, energizing “red mind” stress response to metabolize stress, or to downshift into a more relaxed “green” or “blue mind” state.

23. Incorporate Massage for Rest

Use massage (professional or self-massage, e.g., foot massage) as a method to achieve deep rest and tend to your nervous system, promoting relaxation and cellular repair.

24. Monitor Glucose Temporarily

Consider temporarily using a continuous glucose monitor for a week or two to understand how your body responds to different foods and stressful events, gaining valuable baseline information about your metabolic health.

25. Practice Mindful Eating

Engage in mindful eating practices, especially when dealing with emotional distress or binge eating, to help regulate consumption and reduce the dramatic glucose spikes associated with overeating.

26. Cultivate Pro-Social Joy

Actively engage in pro-social acts to boost positive emotions and stress resilience, such as doing something kind for someone, savoring someone’s joy by asking what made them happy, or looking for opportunities to make someone smile.